Nucleosides and nucleotides in drug discovery

Nucleosides and Nucleotides receive extensive synthetic attention due to their numerous uses in therapeutic and biotechnology applications. Examples include Sofosbuvir1, an important antiviral medication for the treatment of the hepatitis C virus (HCV) which works as a selective inhibitor of HCV NS5B polymerase with a high barrier to viral resistance, and more recently Remdesivir2 for its potential use in the treatment of Covid-19. Concept Life Sciences has unrivaled expertise in the synthesis of nucleosides and nucleosides from route development to synthesis of mg to kg scale.


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