CYP 450 inhibition assay data sheet

Inhibitory potency (IC50) provides invaluable information regarding drug interaction potential. The IC50 of test compound against the five most important drug-metabolizing enzymes is determined using specific drug probe substrates. Analysis is by LC-MSMS.

Deliverable: IC50 (μM) of test compound against CYP1A2, CYP2C9, CYP2C19, CYP2D6 & CYP3A4.

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