MicroCal PEAQ-ITC (from Malvern Instruments) is the most recent model of ITC instrumentation, with enhanced sensitivity, improved washing module, and convenient analysis software compared to previous MicroCal ITC systems. Malvern Instruments has comprehensive manuals and videos to support the use of MicroCal PEAQ-ITC and data analysis. This Technical Note supplements these manuals, and provides additional practical tips that will contribute to improved performance of MicroCal PEAQ-ITC. Use of MicroCal PEAQ-ITC will contribute to the understanding of binding energetics and broaden the application of ITC.

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