Nucleosides and Nucleotides receive extensive synthetic attention due to their numerous uses in therapeutic and biotechnology applications. Examples include Sofosbuvir1, an important antiviral medication for the treatment of the hepatitis C virus (HCV) which works as a selective inhibitor of HCV NS5B polymerase with a high barrier to viral resistance, and more recently Remdesivir2 for its potential use in the treatment of Covid-19. Concept Life Sciences has unrivaled expertise in the synthesis of nucleosides and nucleosides from route development to synthesis of mg to kg scale.