MicroCal range

Microcalorimeters for characterization of biomolecular stability and interactions

MicroCal microcalorimeters are powerful, analytical tools used to study biological systems. These include interactions between molecules as well as changes in conformation such as protein unfolding. The technique is very convenient requiring only minimal assay development and NO labelling. The range includes both Differential Scanning and Isothermal Titration calorimetry.

MicroCal microcalorimeters are used in a wide range of applications from basic research to the discovery and development of small molecule drugs, biotherapeutics and vaccines. Our customers include pharmaceutical, biotech, academic and governmental research institutions worldwide.

Supported products

MicroCal PEAQ-DSC Automated

Gold standard protein stability analysis for the regulated environment

Measurement
Label-free analysis
Protein stability
Sample throughput
Up to to 50per 24h day
Temperature range
2°C to 130°C
Technology
Differential Scanning Calorimetry (DSC)
MicroCal PEAQ-DSC Automated

MicroCal PEAQ-DSC

Gold standard protein stability analysis for research applications

Measurement
Label-free analysis
Protein stability
Sample throughput
Up to to 6per 8h day
Temperature range
2°C to 130°C
Technology
Differential Scanning Calorimetry (DSC)
MicroCal PEAQ-DSC

MicroCal PEAQ-ITC Automated

Fully automated, hands free ITC for increased productivity

Measurement
Label-free analysis
Binding affinity
Temperature range
2°C to 80°C
Sample throughput
Up to to 42per 24h day
Technology
Isothermal Titration Calorimetry (ITC)
MicroCal PEAQ-ITC Automated

MicroCal PEAQ-ITC

The Gold Standard for measuring affinity and stoichiometry

Measurement
Label-free analysis
Binding affinity
Temperature range
2°C to 80°C
Sample throughput
Up to to 12per 8h day
Technology
Isothermal Titration Calorimetry (ITC)
MicroCal PEAQ-ITC

MicroCal iTC200

High sensitivity measurement of all binding parameters

Measurement
Label-free analysis
[Retag / Delete] Microcalorimetry
Temperature range
2°C to 80°C
Sample throughput
8per 8h day to 12per 8h day
Technology
Isothermal Titration Calorimetry (ITC)
MicroCal iTC200

MicroCal VP-ITC

Research insights into biomolecular interactions

Measurement
Label-free analysis
Temperature range
2°C to 80°C
Sample throughput
4 per 8h day to 8per 8h day
Technology
Isothermal Titration Calorimetry (ITC)
MicroCal VP-ITC