MicroCal ITC isothermal titration calorimeters all allow direct, label-free in solution measurement of binding affinity and thermodynamics in a single experiment, enabling the accurate determination of binding constants (KD), reaction stoichiometry (n), enthalpy (ΔH) and entropy (ΔS). This provides a complete thermodynamic profile of the molecular interaction. ITC goes beyond binding affinities and can elucidate the mechanisms underlying molecular interactions.

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Supported products

MicroCal PEAQ-ITC Automated

High productivity measurement of multiple binding parameters.
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Measurement
Label-free analysis
Temperature range
2°C to 80°C
Sample throughput
0 per 24h day to 42per 24h day
Technology
Isothermal Titration Calorimetry (ITC)
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MicroCal PEAQ-ITC

High sensitivity measurement of all binding parameters.
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Measurement
Label-free analysis
Temperature range
2°C to 80°C
Sample throughput
8 per 8h day to 12per 8h day
Technology
Isothermal Titration Calorimetry (ITC)
More information