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NanoSight NS500

The Malvern Panalytical NanoSight NS500 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.

The NS500 provides detailed and intuitive analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type being analyzed. Single particle zeta potential measurements on the NS500 provide inherent high resolution zeta distributions which can be measured simultaneously with other NTA measurements parameters like size, particle concentration and can even operate whilst in fluorescence mode.

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User manuals

Software downloads

05 October 2020

3.44

Capture

    • USB camera support.

Other

    • Improved logging. Instrument log files will no longer be overwritten at the start of each day.

    • Improved handling of corrupt/unreadable video files.

    • New script command for automated/unattended data export.

    • Resolved HASP issues in Windows 10 (Version 2004)

3.44

08 January 2019

3.40

Improvements including:

  • USB camera support
  • Improved logging
  • Improved handling of video files
  • New script commands for data export
3.40

27 July 2018

3.30

Improvements including:

  • New SOP pages
  • CFR
3.30

27 November 2015

3.20

Improved Automation

  • Auto-setup, auto-level, focus-level, and auto-focus script commands available
  • Script command to change experiment filename
  • Make background script commands added
  • Changes to continuous flow SOP scripts to ensure smooth flow

Exports

  • Laser color added to nanolog.csv and other outputs

Interface changes

  • Run button on Recent Measurements page
  • User direction messages for capture and process settings improved
  • User Positions 1 and 2 removed

Additional features

  • Optional CFR feature available – audited operation, secure login, data integrity checking, user level program configuration
  • CFR feature can be enabled by adding feature code to CFR security dongle
  • The CFR feature is available as a chargeable upgrade – Part No. PSS0054 for new builds, Part No. NTA4165 as an upgrade for customers running NTA 3.2 software

Other

  • Extended camera log for diagnostic purposes, can revert to daily usage via nano.ini
3.20

15 June 2015

3.10-I2

Improvements and Features

  • Concentration measurement upgrade option for NS500 and single and multi-laser NS300

Improved Automation

  • Automatic focus available for NS300 and NS500
  • Automatic camera level for all instruments

Data Display and Manipulation

  • Flexible data overlays for line graphs and scatter plots
  • CSV and PDF export options for overlaid data
  • Ability to report concentrations between specific size limits
  • Option to ‘exclude’ regions of particles from the scatter plot
  • Updated display for zeta plots

Interface changes

  • Quick access to recent experiments through dedicated tabbed window
  • Experiments display overlaid graphs and scatterplots on load
  • Improved flexibility and usability for graph settings
  • Filter wheel has its own hardware tab, with customisable buttons
  • Procedure guide for electrode air removal
  • Warnings to remind user of essential hardware checks/maintenance

Additional improvements

  • Refined camera levels to give more suitable settings for brighter particles
  • Refined detection threshold range
  • Speed optimised size distribution algorithm runs up to 20 times faster
  • Refined focus and stage controls for ease-of-use
  • Option to correct viscosity and dilution after making a measurement
  • Improved hardware auto-detection and reconnection menus
3.10-I2

30 March 2015

3.10-I1

Improvements and Features

  • Concentration measurement upgrade option for NS500 and single and multi-laser NS300

Improved Automation

  • Automatic focus available for NS300 and NS500
  • Automatic camera level for all instruments

Data Display and Manipulation

  • Flexible data overlays for line graphs and scatter plots
  • CSV and PDF export options for overlaid data
  • Ability to report concentrations between specific size limits
  • Option to ‘exclude’ regions of particles from the scatter plot
  • Updated display for zeta plots

Interface changes

  • Quick access to recent experiments through dedicated tabbed window
  • Experiments display overlaid graphs and scatterplots on load
  • Improved flexibility and usability for graph settings
  • Filter wheel has its own hardware tab, with customisable buttons
  • Procedure guide for electrode air removal
  • Warnings to remind user of essential hardware checks/maintenance

Additional improvements

  • Refined camera levels to give more suitable settings for brighter particles
  • Refined detection threshold range
  • Speed optimised size distribution algorithm runs up to 20 times faster
  • Refined focus and stage controls for ease-of-use
  • Option to correct viscosity and dilution after making a measurement
  • Improved hardware auto-detection and reconnection menus
3.10-I1

15 July 2014

3.0

Improvements and Features
  • Redesigned interface, focusing around repeat measurements
  • Improved particle size distribution algorithm
  • Automatic, integrated hardware detection and communication
  • Increased compatibility with networked computers
  • Easy setup with new installer package
  • Additional features
  • New file system with less files per experiment
  • Improved particle detection and tracking
  • Improved vibration correction
  • Settings stored in the registry rather than .ini file
3.0

Accessories

NanoSight Sample Assistant

Sample storage and walk-away NTA measurements

The NanoSight Sample Assistant is a 96-well plate-based autosampler accessory with a bespoke software suite allowing for walk-away NTA measurements.

NanoSight syringe pump

The Malvern Panalytical NanoSight syringe pump is available for all Malvern Panalytical NanoSight systems, enabling analysis in constant flow for improved sample statistics and measurement of photo-bleaching fluorescent samples.

Support contract options

Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.

When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.

Help Desk

Training

Software downloads

Malvern Panalytical's service options- choose the right plan for you:

Malvern Panalytical Platinum Plan

For laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.

Malvern Panalytical Gold Plan

Enhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.

Malvern Panalytical Bronze Visit

For laboratories looking to optimize instrument performance, regular preventative maintenance is essential.

Platinum PlanGold PlanBronze Visit
Annual PM/PV Test
yes
yes
no
Telephone / Email Support
yes
yes
no
Priority Response
yes
yes
no
Emergency Breakdown visits*
yes
yes
no
Parts Included
yes
no
no
Technical & Software Support
yes
yes
yes
IQ/OQ (Pharma)***
yes
yes
yes

*including labour & travel costs***available at an additional cost

Contact support