NanoSight NS500

Single particle zeta potential platform with integrated fluidics for automation.

The Malvern Panalytical NanoSight NS500 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.

The NS500 provides detailed and intuitive analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type being analyzed. Single particle zeta potential measurements on the NS500 provide inherent high resolution zeta distributions which can be measured simultaneously with other NTA measurements parameters like size, particle concentration and can even operate whilst in fluorescence mode.

Samples are introduced into the viewing chamber using the integrated fluidics capability. On-screen pump control allows for automatic sample handling, including loading, washing and dilution. Software-controlled motorized optical stages enable rapid relocation and refocusing following cleaning, improving reproducibility. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

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Manuals and software

NanoSight NS500 user manual (English)

Version number:: MAN0513-06-EN-00
Publication date:: February 2016

NanoSight Syringe pump user manual (English)

Version number:: MAN0534-03-EN-00
Publication date:: December 2015

NanoSight Zeta analysis manual (English)

Version number:: MAN0519-03-EN-00
Publication date:: December 2015

NanoSight Autosampler user manual (English)

Version number:: MAN0531-02-EN-00
Publication date:: November 2014

NanoSight NTA software installation manual (English)

Version number:: MAN0515-02-EN-00
Publication date:: July 2014

NanoSight NS500 NTA Software guide (English)

Version number:: MAN0547-01-EN-00
Publication date:: July 2014

NanoSight NTA 2.3 software quick start guide (English)

Version number:: MAN0520-01-EN-00
Publication date:: May 2014

NanoSight NS500 user manual (English)

Version number:: MAN0514-01-EN-00
Publication date:: May 2014

Please select your current version

Version number	Operating system	New features	Language
3.30 (28/03/2018)	Windows 7	Improvements including: New SOP pages CFR	English	Download update
3.20 (27/11/2015)	Windows 7	Improved Automation Auto-setup, auto-level, focus-level, and auto-focus script commands available Script command to change experiment filename Make background script commands added Changes to continuous flow SOP scripts to ensure smooth flow Exports Laser color added to nanolog.csv and other outputs Interface changes Run button on Recent Measurements page User direction messages for capture and process settings improved User Positions 1 and 2 removed Additional features Optional CFR feature available – audited operation, secure login, data integrity checking, user level program configuration CFR feature can be enabled by adding feature code to CFR security dongle The CFR feature is available as a chargeable upgrade – Part No. PSS0054 for new builds, Part No. NTA4165 as an upgrade for customers running NTA 3.2 software Other Extended camera log for diagnostic purposes, can revert to daily usage via nano.ini	English	Download update
3.10-I2 (15/06/2015)	Windows 7	Improvements and Features Concentration measurement upgrade option for NS500 and single and multi-laser NS300 Improved Automation Automatic focus available for NS300 and NS500 Automatic camera level for all instruments Data Display and Manipulation Flexible data overlays for line graphs and scatter plots CSV and PDF export options for overlaid data Ability to report concentrations between specific size limits Option to ‘exclude’ regions of particles from the scatter plot Updated display for zeta plots Interface changes Quick access to recent experiments through dedicated tabbed window Experiments display overlaid graphs and scatterplots on load Improved flexibility and usability for graph settings Filter wheel has its own hardware tab, with customisable buttons Procedure guide for electrode air removal Warnings to remind user of essential hardware checks/maintenance Additional improvements Refined camera levels to give more suitable settings for brighter particles Refined detection threshold range Speed optimised size distribution algorithm runs up to 20 times faster Refined focus and stage controls for ease-of-use Option to correct viscosity and dilution after making a measurement Improved hardware auto-detection and reconnection menus	English	Download update
3.10-I1 (30/03/2015)	Windows 7	Improvements and Features Concentration measurement upgrade option for NS500 and single and multi-laser NS300 Improved Automation Automatic focus available for NS300 and NS500 Automatic camera level for all instruments Data Display and Manipulation Flexible data overlays for line graphs and scatter plots CSV and PDF export options for overlaid data Ability to report concentrations between specific size limits Option to ‘exclude’ regions of particles from the scatter plot Updated display for zeta plots Interface changes Quick access to recent experiments through dedicated tabbed window Experiments display overlaid graphs and scatterplots on load Improved flexibility and usability for graph settings Filter wheel has its own hardware tab, with customisable buttons Procedure guide for electrode air removal Warnings to remind user of essential hardware checks/maintenance Additional improvements Refined camera levels to give more suitable settings for brighter particles Refined detection threshold range Speed optimised size distribution algorithm runs up to 20 times faster Refined focus and stage controls for ease-of-use Option to correct viscosity and dilution after making a measurement Improved hardware auto-detection and reconnection menus	English	Download update
3.0 (15/07/2014)	Windows 7	Improvements and Features Redesigned interface, focusing around repeat measurements Improved particle size distribution algorithm Automatic, integrated hardware detection and communication Increased compatibility with networked computers Easy setup with new installer package Additional features New file system with less files per experiment Improved particle detection and tracking Improved vibration correction Settings stored in the registry rather than .ini file	English	Download update

Support contract options

Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.

When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.

Help Desk

Telephone and email support.
Operators who take responsibility for your call and ensure your query is answered.

Training

User training events

Software downloads

A simple mechanism for receiving updates and new features

Malvern Panalytical's service options- choose the right plan for you:

Malvern Panalytical Platinum Plan

For laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.

Malvern Panalytical Gold Plan

Enhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.

Malvern Panalytical Bronze Visit

For laboratories looking to optimize instrument performance, regular preventative maintenance is essential.

	Platinum Plan	Gold Plan	Bronze Visit
Annual PM/PV Test	yes	yes	no
Telephone / Email Support	yes	yes	no
Priority Response	yes	yes	no
Emergency Breakdown visits*	yes	yes	no
Parts Included	yes	no	no
Technical & Software Support	yes	yes	yes
IQ/OQ (Pharma)***	yes	yes	yes

*including labour & travel costs***available at an additional cost

Contact support

NanoSight NS500

Single particle zeta potential platform with integrated fluidics for automation.

Manuals and software

NanoSight NS500 user manual (English)

NanoSight Syringe pump user manual (English)

NanoSight Zeta analysis manual (English)

NanoSight Autosampler user manual (English)

NanoSight NTA software installation manual (English)

NanoSight NS500 NTA Software guide (English)

NanoSight NTA 2.3 software quick start guide (English)

NanoSight NS500 user manual (English)

Support contract options

Help Desk

Training

Software downloads

Malvern Panalytical's service options- choose the right plan for you:

Malvern Panalytical Platinum Plan

Malvern Panalytical Gold Plan

Malvern Panalytical Bronze Visit

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Malvern Panalytical Support and Services

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