Pharmaceuticals - When size is not enough

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00:00:00 When size is not enough!
00:02:02 When size is not enough!
00:03:38 When size is not enough!
00:05:13 Outline
00:06:35 Particle shape analysis for pharmaceuticals
00:07:37 Shape analysis with automated optical imaging
00:08:23 Particle chemical analysis for pharmaceuticals
00:09:34 Raman spectroscopy coupled with automated optical imaging
00:10:26 Drug delivery
00:10:52 Case study – characterization of drug delivery polymer microspheres with automated optical imaging
00:12:22 Case study – characterization of drug delivery polymer microspheres with automated optical imaging
00:13:09 Characterization of drug delivery polymermicrospheres using the Morphologi® G3SE
00:14:38 Characterization of drug delivery polymermicrospheres using the Morphologi® G3SE
00:15:54 Automation of QC analysis for pharmaceutical ointments
00:16:26 Case study – Automation of QC analysis for pharmaceutical ointments
00:17:47 Case study – Automation of QC analysis for pharmaceutical ointments
00:19:37 Automation of QC analysis for nasal drugs
00:20:34 Case study – Automation of QC analysis for nasal drugs
00:21:44 Case study – Automation of QC analysis for nasal drugs
00:22:58 Automation of Manual QC analysis ofNasal Spray on the Morphologi® G3
00:24:59 Automation of Manual QC analysis ofNasal Spray on the Morphologi® G3
00:26:36 Allergen characterization
00:26:56 Case study – Allergen Characterization
00:27:58 Case study – Allergen Characterization
00:29:02 Characterization of pollen samples withthe Morphologi® G3SE – A case study
00:30:15 Characterization of pollen samples withthe Morphologi® G3SE – A case study
00:32:47 Size and shape of active pharmaceutical ingredients in concentrated suspensions and emulsions
00:33:13 Case study – size and shape analysis of API in concentrated suspensions and emulsions
00:33:26 Case study – size and shape analysis of API in concentrated suspensions and emulsions
00:35:17 Automated analysis of crystals in suspension
00:37:09 In-Vitro Bioequivalence Study with the automated image analysis coupled with Raman spectroscopy
00:38:30 In-Vitro Bioequivalence Study with the G3-ID
00:39:29 In-Vitro Bioequivalence Study with the G3-ID
00:40:24 In-Vitro Bioequivalence Study with the G3-ID
00:41:55 In-Vitro Bioequivalence Study with the G3-ID
00:44:46 In-Vitro Bioequivalence Study with the G3-ID
00:46:33 Other applications of G3-ID
00:47:17 Summary
00:48:07 Contact Information

Particle size has been recognized as a key parameter in the development and manufacture of a wide range of pharmaceutical materials. Sometimes, however, size analysis is just not enough to provide the answer to a specific application issue. This presentation describes the advantages of investigating not only the size but also the shape and chemical signature of various products and formulations. The talk is application based, which means that it doesn't focus on how and what we can measure, but instead on how we can use the information on shape and chemistry to directly influence product performance.