The 249th American Chemical Society national meeting (ACS) will take place at Denver, CO - USA on the 22-26 March 2015
We are hosting free workshop on "New developments in Isothermal Titration Calorimetry from MicroCal" on Wendesday, March 25 from 9:30 AM.
Click here to register for this workshop
Join us at our stand #1107
We look forward to seeing you there!
Pour en savoir plus
New developments in Isothermal Titration Calorimetry from MicroCal
Measurements and characterization of binding interactions between proteins and low-molecular weight ligands are fundamental for drug discovery. Among the most recognized challenges in characterizing binding interactions are (1) the need to accurately assess a wide span of binding affinities (KD) and (2) accurately rank and characterize low-molecular weight (LMW) ligands based on affinity, mechanism of action, and energetics of interaction.
Reliable interpretation of binding data can be complicated by the presence of inactive protein fraction or inaccurate assessment of protein concentration. Assessment of this data can be further hampered by inherent uncertainty in concentration of compound stocks.
This uncertainty results from inaccurate measurement, limited solubility, or potential chemical heterogeneity of the compounds such as presence of enantiomers and isomers.
This workshop will cover the latest development in MicroCal's ITC technology and how it addresses these challenges.