記録された日時: July 11 2017

Duration: 32 minutes 37 seconds

Viscosizer TD is a key component of Malvern’s biopharmaceutical toolset, offering novel capabilities for biophysical characterization in complex solutions, particularly applicable in the early stages of the biopharmaceutical development workflow.

Viscosizer TD provides an orthogonal technique for characterization of molecular size, solution stability and self- association, as well as relative viscosity. Industrial researchers compiling predictive molecular stability profiles for early developability assessment must extrapolate the long-term stability behavior of therapeutic molecules from initial data in order to reduce development risk and cost. The fully-automated Viscosizer TD requires low sample volumes and provides a multivariate dataset output, enabling a more efficient and informed decision-making process.

Table of contents
1. Welcome
00:11
2. Introduction
01:50
3. Viscosizer TD:Protein Stability Characterization Platform
00:05
4. Untitled
00:11
5. Untitled
00:11
6. Untitled
00:12
7. Emerging Market - Towards novel biologics
00:34
8. Emerging Market - Towards novel biologics
00:44
9. Untitled
00:12
10. Untitled
00:19
11. Untitled
00:18
12. Protein stability profiling
00:12
13. Protein stability profiling
00:26
14. Viscosizer TD – Physical stability profiling
00:22
15. Viscosizer TD – Physical stability profiling
00:18
16. Viscosizer TD – Physical stability profiling
00:10
17. Untitled
00:33
18. Viscosizer TD – Instrument
00:16
19. Viscosizer TD – Instrument
00:33
20. Viscosizer TD – Instrument
00:27
21. Viscosizer TD – Instrument
00:28
22. Viscosizer TD – Instrument
00:13
23. Taylor Dispersion Analysis – Size
00:20
24. Taylor Dispersion Analysis – Size
00:50
25. Taylor Dispersion Analysis – Size
00:27
26. Untitled
00:35
27. Untitled
01:00
28. Untitled
00:47
29. Untitled
00:16
30. Taylor Dispersion Analysis – kD
01:28
31. Untitled
01:12
32. Untitled
00:52
33. Poiseuille Flow – Viscosity
00:15
34. Poiseuille Flow – Viscosity
00:14
35. Poiseuille Flow – Viscosity
00:03
36. Poiseuille Flow – Viscosity
00:02
37. Poiseuille Flow – Viscosity
00:04
38. Poiseuille Flow – Viscosity
00:14
39. Poiseuille Flow – Viscosity
00:05
40. Untitled
00:13
41. Measurement Capabilities
00:14
42. Measurement Capabilities
00:05
43. Measurement Capabilities
00:19
44. Untitled
00:20
45. Applications: Early developability screen of mAb candidates using TDA
00:41
46. Applications: Early developability screen of mAb candidates using TDA
00:20
47. Applications: Early developability screen of mAb candidates using TDA
00:18
48. Applications: Early developability screen of mAb candidates using TDA
00:34
49. Applications: Early developability screen of mAb candidates using TDA
00:05
50. Applications: Early developability screen of mAb candidates using TDA
00:05
51. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates
00:15
52. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates
00:38
53. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates
00:47
54. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates
00:05
55. Applications: Peptide- peptide interaction analysis using TDA
00:55
56. Applications: Peptide- peptide interaction analysis using TDA
00:08
57. Applications: Aggregation of cyclodextrin-drug conjugate using TDA analysis
00:33
58. Summary
00:38
59. Any questions?
00:09
60. Thank you for your attentionAny questions?
07:30
61. Thank You!
00:16