Applications of DLS
Typical applications of dynamic light scattering are the characterization of particles, emulsions or molecules which have been dispersed or dissolved in a liquid.
The Brownian motion of particles or molecules in suspension causes laser light to be scattered at different intensities.
Analysis of these intensity fluctuations yields the velocity of the Brownian motion and hence the particle size using the Stokes-Einstein relationship.
DLS technology advantages
Dynamic Light Scattering technology from Malvern Panalytical offers the following advantages:
- Accurate, reliable and repeatable particle size analysis in one or two minutes
- Multi-Angle Dynamic Light Scattering (MADLS) improves the resolution of DLS and provides angular independent size results
- Simple, material-independent measurement of per peak particle concentration
- Mean size only requires knowledge of the viscosity of the liquid
- Simple or no sample preparation, high concentration, turbid samples can be measured directly using NIBS
- Size measurement of sizes from <1 nm to >10 um
- Size measurement of molecules from MW < 1000 Da
- Low volume requirement (as little as 3 µL)
- At-line process systems available for control of nanoparticle manufacture
- Compliance with regulatory standards ISO 13321, ISO 22412, 21 CFR Part 11