Higher resolution particle sizing with Multi-angle Dynamic Light Scattering

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00:00:00 Welcome
00:00:13 Introduction
00:00:55 Higher Resolution DLS with MADLS
00:01:23 Multi-angle dymanic light scattering
00:02:19 Multi-angle dymanic light scattering
00:03:08 DLS and MADLS comparison
00:04:22 DLS and MADLS comparison
00:05:08 Resolution of MADLS
00:05:56 Resolution of MADLS
00:08:04 Example of increased resolution
00:09:25 Example of increased resolution
00:10:14 MADLS Analysis Sequence
00:11:04 MADLS Analysis Sequence
00:11:17 MADLS Analysis Sequence
00:11:51 MADLS Analysis Sequence
00:13:38 Suitability of MADLS
00:13:43 Suitability of MADLS
00:14:02 Suitability of MADLS
00:14:27 Suitability of MADLS
00:16:15 The MDLS result
00:17:39 Applications case study
00:18:45 Applications case study
00:19:23 Applications case study
00:19:49 Applications case study
00:20:14 Applications case study
00:21:04 Micelle formation case study
00:22:07 Micelle formation case study
00:22:38 Micelle formation case study
00:22:54 Micelle formation case study
00:24:02 Further information
00:24:49 Summary

In traditional DLS experiments, the scattered light is detected at a single angle and then auto-correlated to determine the diffusion rate of the particles, and ultimately the particle size distribution. Since the direction and the number of photons scattered depends on the size of the particles, for mixed particle sizes a single angle result may misrepresent the true particle size population. 

Multi-angle dynamic light scattering (MADLS) overcomes many of these drawbacks by automatically combining correlograms from multiple measurement angles to give a robust, angular independent result, with improved resolution, which is suitable for comparison with data from orthogonal techniques. In this webinar we will explain the basic principles behind the MADLS measurement on the Zetasizer Ultra and provide measurement examples.