Centro de conhecimento

IntroductionPolymer solids can have a range of mechanical properties, at one extreme they can be very soft and elastic and at the other they can be immensely strong and rigid. Their mechanical properties can change with external conditions such as temperature and pressure. They can be used for a large range of applications from protective coatings to containers and building materials. The ...

Global demand for graphite is soaring, driven by the clean energy transition to electric cars and battery energy storage systems, as graphite is used to make lithium-ion battery anodes. The properties that make it a great anode material also lends itself to many other innovative areas of research, such as specialist coatings and inks. For a given application, the particle size and particle ...

In the field of protein therapeutics, a protein-polymer conjugation strategy can improve the protein’s clinical potential by overcoming some of the challenges, such as physiochemical instability, immunogenicity and suboptimal circulation half-life.[1][2] This strategy is the covalent modification of a therapeutic protein with a polymer of biological or synthetic origin. A commonly used polymer ...

This technical note discusses DLS method development with the Zetasizer Advance series and highlighted the various factors that need to be considered. These include cell selection, instrument verification, sample preparation, measurement set up and results analysis.

The spectacular success of the Covid-19 vaccines has brought to global attention the potential of mRNA as medicines. It has also helped emphasize for the broader public that there are other types of RNA with a huge therapeutic potential, such as short interfering RNA (siRNA). Although they share the fundamental structure —they are both polymers of ribonucleic acids⁠—there are some notable ...

Modern batteries, like Li-ion, have revolutionized our day-to-day life – from enabling smart mobile devices to pollution-free electric cars and intelligent power-management solutions. Batteries also hold the potential to be economical solutions for mass energy storage, complementing renewable energy resources for power grid applications. Irrespective of the cathode chemistry, which can be ...

In this application note field application scientist, Dr Agatha Rosenthal discusses how the MicroCal PEAQ DSC can be used to analyze the thermal stability of mRNA-LNP formulations.

In this application note, Field Application Scientist Dr Jonathan Mehtala describes how pharmaceutical scientists are using electrophoretic light scattering (ELS) to characterize lipid nanoparticles (LNPs) and why you should be using it. Reflecting on a recent publication that investigates the characterization of viral and non-viral vectors using multiple Malvern Panalytical technologies, ...

A recent publication investigates the characterization of viral and non-viral vectors using multiple Malvern Panalytical technologies. This application note takes a close look at how NanoSight NS300 easily can provide a more detailed understanding of a sample’s size distribution and at the same time inform us on the concentration of the different populations in the sample.

X-ray diffraction (XRD) is a powerful tool for studying cultural heritage objects. By identifying crystalline pigments, it can determine the materials used, whether alteration or corrosion has taken place, how the objects were made, and their originality. To protect and preserve the artifacts, this analysis must be non-destructive. When working with smaller-sized objects, researchers often ...