Centro de conhecimento

Specialized immunohistochemical staining approaches utilized during preclinical and clinical drug discovery research provide valuable insights into the location and positioning of immuno-oncology biomarkers within the tumor and the tumor microenvironment (TME). We deliver powerful multiplex immunohistochemical and RNAscope tissue staining and probing services, using a range of specialized techniques, including automated multiplex immunofluorescence (IF) and colorimetric immunohistochemistry (IHC), and RNAscope (in situ hybridization for mRNA). We were Europe's first ACD Bio accredited service provider. Find out how a pragmatic approach to antibody selection and validation can facilitate demonstration of novel and challenging immuno-oncology biomarkers in situ, providing high-value data to complement functional in vitro assay data and inform cancer immunotherapy clinical trial strategy. Please login or register for free to download the poster.

Paints and coatings are highly complex multi-component systems that pose many challenges for the formulation chemist. Ongoing control of raw materials and final formulations is essential for ensuring product quality and customer satisfaction, while an in-depth understanding of physical properties is necessary to devise new formulations. This white paper discusses these challenges, and explains how obtaining information on the constituents of paint at the molecular and particle level using the techniques of X-ray fluorescence (XRF), X-ray diffraction (XRD), laser diffraction (LD), electrophoretic light scattering (ELS), gel permeation chromatography (GPC) (more generally known as size exclusion chromatography (SEC)), and particle image analysis can ultimately lead to better product performance, streamlined operations, and greater value to the business. Please login or register to download.