Fecha registrada: September 09 2010

Duration: 49 minutes 36 seconds

This presentation describes the positioning and usage of SEC as a technique in the bio-pharmaceutical industry. Common uses, regulatory requirements and standards, and the latest detector technology are discussed along with application examples.
Table of contents
1. Size-exclusion chromatography in the modern bio-pharmaceutical laboratory
02:09
2. Size-exclusion chromatography in the modern bio-pharmaceutical laboratory Uses, requirements, technologies and applications
00:43
3. Protein therapeutics
01:29
4. Pharmaceutical Drug Development Pipeline
01:38
5. Protein Characterisation
01:11
6. Current uses of SEC - analytical
03:11
7. Current uses of SEC - QC
01:38
8. Multi-detector Analytical SEC
00:58
9. UV Detection
00:26
10. RI Detection
00:58
11. Static Light Scattering – Molecular Weight
00:59
12. Intrinsic Viscosity
01:15
13. Analytical SEC Chromatogram
01:17
14. Advanced analytical SEC
01:18
15. GPC in QC (qGPC)
00:33
16. Protein Aggregation
00:37
17. Oligomerization vs. aggregation
01:49
18. Aggregated BSA experiments
00:47
19. Aggregated BSA experiments – SEC LS
02:23
20. Aggregated BSA experiments
02:42
21. Qualitative aggregate detection
01:11
22. Current uses of SEC in QC
00:25
23. What more information can be collected?
00:26
24. What data can be provided?
04:34
25. Therapeutic protein sample
01:27
26. Analytical SEC
00:30
27. Molecular weight and oligomeric state
00:41
28. Conformational changes
02:54
29. Case Study – Membrane Protein
01:35
30. Membrane Protein
01:47
31. Drug Delivery Polymer
01:43
32. Summary
03:25
33. Contact Information
00:57