| 00:00:00 | Untitled |
| 00:00:15 | Untitled |
| 00:00:58 | Particle sizing masterclass: How to set meaningful particle size specifications |
| 00:01:14 | Overview |
| 00:01:56 | What is a specification? |
| 00:02:51 | What is a specification? |
| 00:03:46 | Why do we measure particle size? |
| 00:05:08 | Why do we measure particle size? |
| 00:06:05 | Guidance from the pharmaceutical industry |
| 00:06:56 | How to justify specifications |
| 00:07:01 | Which particle size parameter should I use? |
| 00:07:40 | Distribution type & sensitivity |
| 00:09:28 | Particle size distribution statistics |
| 00:09:58 | Particle size distribution statistics |
| 00:11:05 | Particle size distribution statistics |
| 00:12:11 | Choosing the right parameter |
| 00:12:34 | Choosing the right parameter |
| 00:13:12 | Choosing the right parameter |
| 00:13:17 | Choosing the right parameter |
| 00:14:33 | Measurement precision |
| 00:14:45 | Definition of measurement precision |
| 00:16:12 | What factors affect measurement precision? |
| 00:17:07 | Measurement precision - sampling |
| 00:18:01 | Measurement precision - sampling |
| 00:18:31 | Measurement precision - sampling |
| 00:19:24 | What precision values are reasonable |
| 00:21:25 | Measurement variability |
| 00:22:24 | Measurement variability |
| 00:23:38 | How does measurement precision affect the spec? |
| 00:23:43 | How does measurement precision affect the spec? |
| 00:24:24 | Specification example:Tableting |
| 00:24:29 | Factors affecting the tableting process |
| 00:25:48 | Specification example: Tablet formulation |
| 00:26:53 | Specification example: Tablet formulation |
| 00:28:02 | Specification example: Tablet formulation |
| 00:29:26 | Specification example: Tablet formulation |
| 00:30:06 | Conclusions |
| 00:31:23 | Thank you for your attention! |
| 00:38:23 | Untitled |
The most important thing when setting a specification is to relate it to why you need to measure particle size. For example, what aspect of product performance, or what part of the manufacturing process, are you trying to control?
In this webinar we will look at how to choose the appropriate particle size parameter to specify product performance. To achieve this, we will describe some of the range of parameters calculated from the particle size distribution, and how they can be used with appropriate tolerances to provide robust specifications.