| 00:00:00 | Tabletting - a modern approach |
| 00:02:21 | Tablets/tabletting (or is it tableting?) |
| 00:02:53 | Overview |
| 00:04:32 | Abstract |
| 00:05:12 | Aspirin Life Magazine October 22, 1945 page 69 |
| 00:06:43 | Plagiarism |
| 00:07:12 | Advantages of tablets |
| 00:08:15 | Advantages of tablets |
| 00:08:44 | Disadvantages of tablets |
| 00:09:31 | The beginnings of tablets |
| 00:10:33 | The beginnings of tablets |
| 00:11:22 | The beginnings of tablets Remington Tablet Machine Circa 1875 |
| 00:11:57 | Stages in Compaction |
| 00:12:48 | Plastic Flow or Brittle Fracture? |
| 00:13:44 | Plastic Flow or Brittle Fracture? |
| 00:14:55 | Lubricants |
| 00:16:50 | Ideal properties for a direct compression excipient |
| 00:17:29 | Direct compression excipient |
| 00:18:45 | Compressibility |
| 00:19:27 | Tabletability |
| 00:19:52 | Compactibility |
| 00:21:16 | Stages in tabletting |
| 00:22:34 | Wet granulation - advantages |
| 00:23:18 | Wet granulation - disadvantages |
| 00:23:53 | Dry/direct compaction |
| 00:24:28 | Dry/direct compaction Disadvantages |
| 00:25:37 | Factors Influencing Dispersion Rheology |
| 00:26:19 | Untitled |
| 00:26:42 | Untitled |
| 00:27:37 | Untitled |
| 00:28:06 | Effect of Particle Shape |
| 00:28:57 | Materials |
| 00:29:24 | Materials Particle Size |
| 00:30:10 | Adhesion force |
| 00:31:18 | Materials Particle size distributions |
| 00:32:30 | Materials Particle Size Distribution |
| 00:33:02 | Where do the materials go after compression? |
| 00:34:43 | Malvern: From Particles to Tablets |
| 00:34:55 | NIR Chemical Imaging |
| 00:35:37 | SynIRgi |
| 00:36:02 | Content uniformity |
| 00:36:59 | Materials – theory Hersey - 1970 |
| 00:37:40 | Heckel theory – most useful |
| 00:37:56 | Methodology |
| 00:38:51 | Particle shape |
| 00:39:37 | Other properties |
| 00:39:59 | Untitled |
| 00:40:32 | Shangraw, et. al., Pharmaceutical Technology Formulators’ preference for certain fillers/binders |
| 00:40:54 | Formulators’ preference for disintegrating agents |
| 00:41:17 | Formulators’ preference for certain lubricant levels |
| 00:41:38 | Excipients for direct compression |
| 00:42:14 | Key Factors: Particle Size and Shape |
| 00:42:57 | Ideal Material |
| 00:44:10 | Effects of Physical Properties for Starch Acetate Powders on Tableting* |
| 00:44:54 | Physical Properties and Compact Analysis of Commonly Used Direct Compression Binders* |
| 00:45:33 | Effect of Particle Size on Tablet Strength* |
| 00:45:55 | Common problems encountered during tablet manufacturing operations include |
| 00:46:45 | Determining factors for particle size of a tablet formulation |
| 00:47:10 | Determining factors for particle size of a tablet formulation |
| 00:47:31 | Fines |
| 00:48:14 | Untitled |
This webinar describes the particle sizing needs for tabletting and the effect changes in particle size can have on the end product.