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응용 노트

18 September 2023 | English

Overcoming challenges in LNP vector analysis: key tools, techniques, and considerations

In this eBook, Malvern Panalytical will guide you through the different challenges, technologies and solutions facing LNP vector analysis. This information can help empower everything from vector design through formulation development and manufacturing, enabling more confident decision-making for faster delivery of better medicines to patients in need.

제품:
MicroCal DSC 시리즈, Zetasizer Ultra, Zetasizer Advance Range, NanoSight Pro, OMNISEC 시스템
기술 유형:
동적 광산란, 시차 주사 열량측정법(DSC), 전기영동 광산란, 크기 배제 크래마토그래피 (SEC), 나노 입자 추적 분석, Multi-Angle Dynamic Light Scattering (MADLS)
산업:
생물제제, 정부/기관, 학술, 대학교, 제약
Overcoming challenges in LNP vector analysis: key tools, techniques, and considerations
포스터

15 September 2023 | English

Kinetic screening using Grating-Coupled Interferometry (GCI)

GCI is ideally suited for fragment-based drug discovery due to inherent sensitivity of the detection principle, and the ability to capture fast transitions. Here we show a collection of challenging target classes across a variety of fragment-based drug discovery campaigns where GCI was used to screen fragment libraries (~ 1100 compounds). Hits were picked based on statistical errors and kinetic ...

제품:
Creoptix WAVE
기술 유형:
Microfluidics, Grating-coupled interferometry (GCI)
산업:
생물제제, 제약
Kinetic screening using Grating-Coupled Interferometry (GCI)
화이트 페이퍼

15 September 2023 | English

Next-level flexibility for drug discovery

The interaction between compounds and their drug targets – particularly the binding kinetics – is an essential part of the identification and validation of new therapeutics and small-molecule drugs. But, despite the many technological advances in research and development, many challenges remain in using kinetic analysis for the early stages of drug discovery. In this whitepaper, we aim to ...

제품:
Creoptix WAVE
기술 유형:
Microfluidics, Grating-coupled interferometry (GCI)
측정 유형:
비표지(label-free) 분석법, Association Constant, Dissociation Constant, 결합 친화도, 결합 반응 속도, 분자량, 분자 크기
Next-level flexibility for drug discovery
기술노트

13 September 2023 | English

NanoSight NS300 Tube Configurations

Since the NS300 has been reclassified as a Class 3R laser product, the aperture in the instrument case must be covered. The NS300 was originally shipped with a bulkhead tubing connector. This was often removed and misplaced. We are now offering a cheaper 3D printed tube slot which is much easier to use. It is recommended that any user who has no bulkhead connector fitted order this replacement ...

제품:
NanoSight NS300
기술 유형:
나노 입자 추적 분석
NanoSight NS300 Tube Configurations