Biophysical characterization of viral and lipid-based vectors for vaccines and therapeutics with light scattering techniques

The structural complexity of viral vectors and lipid nanoparticles (LNPs) is integral to their function and successful formulation. Particle characterization is becoming increasingly important when such molecules are used as delivery platforms for nucleic acids (mRNA, DNA). During design, product development and process, characterization and quality control of physical and chemical attributes requires fit-for-purpose and complementary analytical tools.

In this poster, scientists from Malvern Panalytical present a range of complementary, label-free biophysical techniques that have been successfully used to characterize the physical and chemical attributes of viral vectors and LNPs encapsulating mRNA.

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The structural complexity of viral vectors and lipid nanoparticles (LNPs) is integral to their function and successful formulation. Particle characterization is becoming increasingly important when such molecules are used as delivery platforms for nucleic acids (mRNA, DNA). During design, product development and process, characterization and quality control of physical and chemical attributes requires fit-for-purpose and complementary analytical tools.

In this poster, scientists from Malvern Panalytical present a range of complementary, label-free biophysical techniques that have been successfully used to characterize the physical and chemical attributes of viral vectors and LNPs encapsulating mRNA.

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