Ask an expert ! - ITC for organic solvents: Tips for success with this trending application in chemistry and life sciences

There is increasing interest in Isothermal Titration Calorimetry (ITC) applications that require dissolving the binding partners in an organic solvent. These include studying guest-host chemical reactions, interactions involving nanoparticles, and characterizing normally insoluble materials. For successful results, the ITC experimental protocol with organic solvents requires minor modification of the normal methods with aqueous buffers. This webinar will discuss the best practices for using organic solvents with MicroCal ITC systems, including the PEAQ-ITC, iTC200, and VP-ITC. These suggestions will help improve the data quality and avoid damaging the ITC instrument. 

Presenters include research scientists who routinely incorporate organic solvents in their ITC experiments, as well as ITC experts with Malvern Panalytical. 

This webinar is part of our ‘Ask an expert’ webinar series. These live webinars are meant for students and research scientists who want to sharpen their analytical methods, deepen their knowledge, or find out how to improve their data. We’ll provide extensive materials analysis information and answer your most frequently asked questions. In other words, it’s the ultimate way to improve your knowledge.


  • Gloria Tobajas Curiel - PhD Student - University of Cambridge, UK 
  • Angus Yeung - PhD Student - University of Birmingham, UK 
  • Raul Pacheco Gomez - Field Application Specialist - Malvern Panalytical 
  • Verna Frasca - Sector Development Manager - Pharma & Food - Malvern Panalytical

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Who should attend?

Students and research scientists in academia and the pharmaceutical industry, working in the field of biomolecular science and engineering, who are interested in improving their knowledge with our analytical solutions.

What will I learn?

  • Experimental practicalities as well as how to obtain quality data will be covered.
  • Information on chemical resistance and what solvents to avoid when using an ITC instrument