Fragment screening of GPCRs using Grating Coupled Interferometry (GCI) technology

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GPCRs are notoriously difficult to study, due to their intrinsic protein instability. By utilizing the sensitivity of Grating Coupled Interferometry (GCI) technology combined with non-clog microfluidics, these pesky membrane proteins can be analyzed.

Evotec, a life science company who is committed to advancing drug discovery and development through their collaborations with biotech, pharma, foundations, academia and government agencies, have successfully harnessed Grating Coupled Interferometry (GCI) for the fragment screening of GPCRs.


  • Edoardo Fabini - Principal Scientist, Evotec
  • Edward Fitzgerald - Segment Lead - Drug Discovery, Malvern Panalytical

Pour en savoir plus

What will you learn? 

  • What are GPCRs and why study them
  • Challenges in studying GPCRs
  • Evotec’s solution to studying GPCRs using GCI technology
  • A summary of Evotec’s workflow and data covering:
    • Assay development
    • Fragment screening
    • Binding confirmation

Who should attend? 

If you are still reading, the webinar is for you!  

  • Scientists and researchers interested in small molecule/fragment screening using state-of-the-art biophysics
  • Anyone interested in or working in Drug Discovery