Zeta potential - An important parameter for controlling formulation stability and product performance

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00:00:00 Welcome
00:00:24 Untitled
00:00:57 Zeta PotentialAn important Parameter for Controlling Formulation Stability and Product PerformanceAna Morfesis, Ph.D. ana.morfesis@malvern.com
00:01:28 Untitled
00:01:33 Formulated Products - Applications
00:03:22 Multicomponent Products & Film Formation
00:06:54 Untitled
00:07:00 What is Zeta Potential?
00:08:09 DLVO Theory, 1940’s
00:10:42 Zeta Potential
00:14:27 Untitled
00:16:01 ELECTROSTATICS:Origins of Surface Charge in Aqueous Media
00:16:15 Untitled
00:20:52 Polymer Adsorption
00:24:13 Untitled
00:24:26 Formulations
00:26:57 Simple 3 Component Example > Zeta Potential provides a measurement method to study the Role of the Components
00:28:59 Direction for Developing New Coating Materials Surface Activity of Surfactant
00:30:37 Reduced Product VariabilityCoating Defects
00:31:59 Coating Efficiency
00:33:03 Mix Order of Coatings
00:34:59 Untitled
00:35:05 Electrophoretic Light Scattering
00:36:13 Zeta Potential
00:36:55 Henry’s Function F(ka)
00:39:08 Electrophoretic Light Scattering(Zeta Potential)
00:40:43 Optical Configuration
00:41:49 Example Measurement Cells Capillary & Dip Cells
00:44:24 Conclusion
00:46:11 Thank you for your attentionAny questions?Please type your questions in using the Q&A panel on the right side of your screen
00:46:36 Untitled
Cosmetics, paints, inks, paper, drug delivery, personal care, food or intra-lipid emulsions are made up of multi component chemistries. Most products go through a stage where different phases co-exist such as emulsions, suspensions or dispersions and as such require a specific amount of stability in order to meet expected performance criteria.

Performance requirements may include ease of spreading for a paint in order to produce a thin even film on the substrate, or limited spreading in the case of inks used in high resolution printing where good dot resolution is required. For lipsticks and sunscreens even-film coverage is an important performance metric and requires the dispersed components to remain discrete and not to aggregate during application. Cough syrups, drug suspensions or food dispersions must maintain stability when stored on the shelf to prevent settling or creaming.

An important predictor of dispersion stability is the zeta potential which is a measure of the degree of electrostatic repulsion or attraction in a colloidal system and can determine whether a mixture of specific chemistries are compatible with each other or not. Zeta potential measurements provide information about the surface/interfacial chemistry of individual components in formulated products and how those chemical components interact when mixed together.

In this webinar Dr Ana Morfesis gives an overview of zeta potential and its measurement and explain how this important parameter can be used in product development to enhance product stability and performance.