Wissensdatenbank

Polycaprolactone (PCL) is a synthetic polymer that has recently received increasing attention thanks to its biodegradability. Its most common use is in the manufacture of polyurethanes or as a plasticizer for other polymers such as PVC. It is also often used in molding and prototyping thanks to its low melting temperature and is used as a feedstock in some additive manufacturing (3D printing) systems. Finally, it is also used in some drug delivery applications as a control release mechanism, in the same way as polylactic acid (PLA) or polylactic-co-glycolic acid (PLGA). A potential advantage over PLA and PLGA is that PCL has a slower degradation rate and therefore may allow for slower drug release.. As with all polymers, PCL’s molecular properties (e.g. molecular weight) will strongly affect its bulk properties such as strength, toughness, and melt-flow. Being biodegradable, PCL is at a high risk of degradation during processes such as extrusion for molding, particularly at high temperatures. Some mechanisms have been described in the literature to reduce this. For instance, extrusion in the presence of carbon dioxide (CO2) can reduce the melt flow viscosity of PCL by acting as a ‘molecular lubricant’. Decreasing the viscosity of the polymer reduces the temperature at which extrusion can be performed and could thereby protect the polymer from degradation during the process [1].. In this application note, a commercially available sample of PCL was extruded alone and in the presence of CO2­. Multi-detector GPC measurements were made of the virgin sample before and after extrusion, while rotational rheometry was used to study the polymer’s melt viscosity..

Produkte:

Kinexus lab+

Datum:

April 27 2017

Sprache:

English

The Zetasizer Nano ZS can measure the size, MW, the second virial coefficient and the zeta potential of macromolecules such as antibodies. The light scattering technology used is ideal for the characterization of the antibody fragment (Fab).

Produkte:

Zetasizer Nano Linie

Datum:

October 9 2003

Sprache:

English

In this note we analyze two hyperbranched polyesters samples by advanced size exclusion chromatography to assess the branching. We show that even for low dn/dc samples of hyperbranched polyesters the results are reproducible

Produkte:

Viscotek Linie

Datum:

September 30 2009

Sprache:

English

The triple detector size exclusion chromatography system is ideal for polymer structure analysis because it directly detects changes in polymer structure as well as molecular weight, whereas conventional methods detect only differences in size

Produkte:

Viscotek Linie

Datum:

September 30 2009

Sprache:

English

The Viscotek Dilute Solution Viscosity (DSV) system provides fully automated determination of the viscosity of polyethylene terephthalate (PET) resins, with safety, precision, and accuracy

Produkte:

Viscotek Linie

Datum:

September 30 2009

Sprache:

English