Fecha registrada: October 07 2010

Duration: 54 minutes 19 seconds

This webinar describes the particle sizing needs for tabletting and the effect changes in particle size can have on the end product.
Table of contents
1. Tabletting - a modern approach
02:21
2. Tablets/tabletting (or is it tableting?)
00:32
3. Overview
01:39
4. Abstract
00:40
5. Aspirin Life Magazine October 22, 1945 page 69
01:31
6. Plagiarism
00:29
7. Advantages of tablets
01:03
8. Advantages of tablets
00:29
9. Disadvantages of tablets
00:47
10. The beginnings of tablets
01:02
11. The beginnings of tablets
00:49
12. The beginnings of tablets Remington Tablet Machine Circa 1875
00:35
13. Stages in Compaction
00:51
14. Plastic Flow or Brittle Fracture?
00:56
15. Plastic Flow or Brittle Fracture?
01:11
16. Lubricants
01:55
17. Ideal properties for a direct compression excipient
00:39
18. Direct compression excipient
01:16
19. Compressibility
00:42
20. Tabletability
00:25
21. Compactibility
01:24
22. Stages in tabletting
01:18
23. Wet granulation - advantages
00:44
24. Wet granulation - disadvantages
00:35
25. Dry/direct compaction
00:35
26. Dry/direct compaction Disadvantages
01:09
27. Factors Influencing Dispersion Rheology
00:42
28. Untitled
00:23
29. Untitled
00:55
30. Untitled
00:29
31. Effect of Particle Shape
00:51
32. Materials
00:27
33. Materials Particle Size
00:46
34. Adhesion force
01:08
35. Materials Particle size distributions
01:12
36. Materials Particle Size Distribution
00:32
37. Where do the materials go after compression?
01:41
38. Malvern: From Particles to Tablets
00:12
39. NIR Chemical Imaging
00:42
40. SynIRgi
00:25
41. Content uniformity
00:57
42. Materials – theory Hersey - 1970
00:41
43. Heckel theory – most useful
00:16
44. Methodology
00:55
45. Particle shape
00:46
46. Other properties
00:22
47. Untitled
00:33
48. Shangraw, et. al., Pharmaceutical Technology Formulators’ preference for certain fillers/binders
00:22
49. Formulators’ preference for disintegrating agents
00:23
50. Formulators’ preference for certain lubricant levels
00:21
51. Excipients for direct compression
00:36
52. Key Factors: Particle Size and Shape
00:43
53. Ideal Material
01:13
54. Effects of Physical Properties for Starch Acetate Powders on Tableting*
00:44
55. Physical Properties and Compact Analysis of Commonly Used Direct Compression Binders*
00:39
56. Effect of Particle Size on Tablet Strength*
00:22
57. Common problems encountered during tablet manufacturing operations include
00:50
58. Determining factors for particle size of a tablet formulation
00:25
59. Determining factors for particle size of a tablet formulation
00:21
60. Fines
00:43
61. Untitled
06:05