Fecha registrada: August 25 2011

Duration: 43 minutes 07 seconds

This presentation will provide an overview of the different applications of automated particle imaging within the pharmaceutical research, development and production environments. This will be illustrated with a wide range of application examples.
Table of contents
1. Particle characterisation using Morphological imaging: Pharmaceutical applications
02:19
2. Overview
01:12
3. What is Morphological Imaging?
01:03
4. Why is particle size and shape important ?
01:11
5. Malvern Instrumentation
01:42
6. Morphological Imaging in the Pharmaceutical Development Cycle
02:28
7. Value of imaging to pharmaceutical industry
01:36
8. Application data Trouble shooting / manufacturing support - identifying batch differences
00:11
9. Difference in behaviour between Tap Milled vs Micronised excipient
00:46
10. Difference in Behavior
00:57
11. API Dissolution behaviour - Batch-to-batch
00:35
12. API Dissolution behaviour - Batch-to-batch
00:50
13. Identify Parameters that differentiate between Good and Bad Batches
01:44
14. Application data Research and Development
00:11
15. Assess Effect of dispersion pressure
00:54
16. Assess Effect of Dispersion Pressure
00:54
17. Assess Effect of dispersion pressure
00:46
18. Assess Effect of dispersion pressure
00:46
19. Assess Effect of dispersion pressure
00:29
20. Effect of Dispersion Conditions – Fragile APIs
00:49
21. Application data Regulation and Quality Control
00:04
22. Foreign Particulate Matter (FPM)
01:20
23. Parenterals USP 788 – Standard Report
00:37
24. QC - Identify Oversized API particles in Drug Suspension
01:02
25. QC - Identify Oversized API particles in Drug Suspension
00:26
26. QC – Biotherapeutics suspension
01:08
27. Application data Measuring individual components with in a formulation
00:06
28. Crystalline and Amorphous API
00:48
29. Crystalline and Amorphous API
00:56
30. Mixture of API and Starch
00:59
31. Application data Measuring PSD of the API in a formulation for Bioequivalence Comparisons
00:12
32. Nasal Spray – API Particle Size Distribution
01:20
33. Nasal Spray – API Particle Size Distribution
01:22
34. Nasal spray – Additional Verification by Morphologically Directed Raman Spectroscopy
01:44
35. Nasal Spray Formulation – API Size Distribution
00:11
36. Assess Bioequivalence Anti-inflammatory cream
00:42
37. Assess Bioequivalence: Injectable formulation
00:59
38. Application data Validating other sizing techniques
00:07
39. Validating other sizing techniques
01:23
40. Validating other sizing techniques
01:13
41. Validating other sizing techniques
00:40
42. Validating other sizing techniques
00:32
43. Validating other sizing techniques
00:32
44. Validating other sizing techniques
01:11
45. Summary
00:57
46. Contact Information
01:13