Pushing the limits of DLS: Measuring large particles on the Zetasizer Ultra with the Low-Volume Sizing Cell

Dynamic Light Scattering (DLS) allows the hydrodynamic size of particles in  dispersion to be measured by quantifying their diffusive motion. At particle sizes approaching the upper size range for DLS, sedimentation, thermal currents and number fluctuations can mean that the detected scattering no longer accurately describes purely diffusive motion, and particle size analysis becomes less accurate. Here we will discuss how the Low Volume Disposable Sizing Cell can improve data quality at large particle sizes and allow the entire size range of DLS to be explored without modification of the dispersant system.

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