This note compares the use of three different methods – X-ray diffraction, near infrared spectroscopy and differential scanning calorimetry – for quantifying small amounts of amorphous material in a crystalline matrix, and vice versa.
In this investigation we used alphalactose monohydrate as a model substance. In the pharmaceutical
industry this material is widely employed as a filler and diluent in tablets and capsules, as a carrier substance in dry powder inhalers and as a lyoprotectant during the freeze-drying of proteins.
Pas encore inscrit?
Sign up for free today. By registering you will have free access to exclusive content including
- Webinars, presentations and videos
- Application notes, technical notes, articles, white papers and software downloads
And in addition you will receive
- Our regular eNews including the latest news, education, events and offers from Malvern Panalytical