Molecular weight determination of polymers and polysaccharides using the Zetasizer Nano

Static light scattering can be used to measure the molecular weight of macromolecules such as proteins and polysaccharides, as well as their virial coefficients to determine intermolecular interactions. This application note details molecular weight measurements performed on various proteins, polymers and polysaccharides on the Zetasizer Nano. Data from Polystyrene [10kDa, 100kDa, 980kDa] in toluene and dextrane [63kDa] in water are shown as representative examples.


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