Size and zeta potential characterization of liposomes using the Zetasizer Nano

Liposomes are used as a vehicle for intravenously delivered drugs, gene therapy and functional cosmetics. Measurement of the size and zeta potential can be used to increase retention in the body, and develop aggregation resistant formulations. Special categories are small unilamellar vesicles SUV, large unilamellar vesicles LUV, multilamellar vesicles MLV.

Size and zeta potential of liposomes play an important role for designing drug delivery vehicles such as for small interfering RNA siRNA or messenger RNA mRNA gene delivery.


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