Date d'enregistrement: April 11 2019

Duration: 40 minutes 25 seconds

Dolomite Microfluidics specializes in the production of high-performance nano- and microparticles which are precision-engineered for advanced functionality and encapsulation. These materials have unique properties determined by their size, shape and architecture which enable them to be used as specialized research tools within biomedicine, diagnostic imaging and industrial catalysis. At Dolomite Microfluidics, state-of-the-art automated continuous flow processing and droplet microfluidics are used to ensure very monodisperse particles with high batch-to-batch consistency.

This webinar explores the combined use of the Malvern Panalytical Zetasizer Ultra and the Dolomite Microfluidics system to generate drug-encapsulating nanoparticles with improved monodispersity and higher encapsulation efficiency, and with better reproducibility than a batch system. The Dolomite Microfluidics system enables very precise control of the size and composition of the nanoparticles. Applying the Zetasizer Ultra to characterize the nanoparticles enables faster and less expensive development of the microfluidic methodologies, due to the instrument’s unique Multi Angle DLS (MADLS) capabilities. MADLS provides the speed and size resolution needed to identify distinct populations, allowing quick iteration and consistent production of nanoparticles of a very high quality.

Table of contents
1. Improving the development efficiency of drug-encapsulating nanoparticles using microfluidics and Multi-Angle Dynamic Light Scattering (MADLS)
02:45
2. Drug Encapsulation and the Zetasizer Ultra
00:36
3. Drug Encapsulation and the Zetasizer Ultra
01:32
4. Methods of Encapsulation
02:00
5. Methods of Encapsulation
00:00
6. Methods of Encapsulation
03:02
7. Methods of Encapsulation
01:24
8. Methods of Encapsulation
00:52
9. Untitled
02:44
10. Typical Methods of Characterization
03:12
11. Zetasizer Ultra
01:12
12. Multi Angle Dynamic Light Scattering
00:41
13. Multi Angle Dynamic Light Scattering
00:28
14. Multi Angle Dynamic Light Scattering
00:20
15. How MADLS Improved Development Efficiency
00:21
16. How MADLS Improved Development Efficiency
00:39
17. A typical day in the lab – before microfluidics and MADLS
03:29
18. A typical day in the lab – after microfluidics and MADLS
00:54
19. Summary
00:37
20. Thank you for your attentionQuestion & Answer SessionListening live:Ask your question by typing within the Q & A chat facility Listening on-demand:Send your questions toevents@malvernpanalytical.com
13:37