Nanotechnology and oncology

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00:00:00 Nanotechnology and oncology
00:01:52 Nanotechnology and oncology
00:02:41 Abstract
00:03:07 One hope – Press release: http://tinyurl.com/a3dzh4a
00:04:43 Careful with the hype – nanobotsRemember the basics…..
00:05:25 What is cancer? See: http://www.cancer.gov/
00:06:08 Statistics
00:07:14 Balanced scorecardhttp://progressreport.cancer.gov/trends-glance.asp
00:08:13 Types
00:09:00 The Good News
00:10:11 Nanotechnology
00:11:22 Cancer Nanotechnology
00:12:45 Solubility
00:13:32 Solubility
00:14:41 Figure 2 - Factors that lead to increased solubility and permeability of Class II and IV, and Class III drugs
00:15:38 “The magic bullet”
00:16:22 Diversion: The original magic bullet
00:17:35 Dendrimers
00:18:51 Active TargetingMTX = methotrexate. It can be conjugated to a G5 PAMAM dendrimer
00:19:53 Drug or Device?
00:20:04 Size Matters
00:21:05 Mauro Ferrari “CANCER NANOTECHNOLOGY: OPPORTUNITIES AND CHALLENGES” NATURE REVIEWS | CANCER VOLUME 5 | MARCH 2005 | 161
00:21:49 The potential
00:22:36 Nanotechnology and BiologyWhy?
00:23:41 Untitled
00:24:00 One potential application
00:25:04 Jennifer H. Grossman. Scott E. McNeil “Nanotechnology in Cancer Medicine”Phys. Today 65(8), 38 (2012); doi: 10.1063/PT.3.1678
00:25:51 M M Yallapu, M Jaggi, S C Chauhan “Scope of nanotechnology in ovarian cancer therapeutics” Journal of Ovarian Research , 3:19 (2010)
00:26:41 Nanomedicine Pipeline
00:27:06 S A Mousa, D J Bharali “Nanotechnology-Based Detection and Targeted Therapy in Cancer: Nano-Bio Paradigms and Applications” Cancers 2011, 3, 2888-2903; doi:10.3390/cancers3032888
00:27:32 S A Mousa, D J Bharali “Nanotechnology-Based Detection and Targeted Therapy in Cancer: Nano-Bio Paradigms and Applications” Cancers 2011, 3, 2888-2903; doi:10.3390/cancers3032888
00:28:33 The big picture$
00:29:13 PCA’sNote 4
00:30:18 What did ANSI-NSP say in 2004? (The unreadable slide!)
00:30:34 ANSI-NSP (Summary/Readable)
00:31:28 NNI - http://www.nano.gov/node/748
00:31:58 What is the NNI?
00:33:04 NNI - Program Areas
00:33:50 The US perspectiveNational Cancer Institute
00:34:38 The big picture
00:35:03 The big picture
00:35:41 Centers of Cancer Nanotechnology Excellence
00:36:12 NCI Alliance
00:36:31 NCI
00:37:20 NCI - successes
00:38:23 TONIC et al
00:39:01 Training programs
00:39:28 Untitled
00:40:23 NCI Alliance for Nanotechnology in Cancer Goals: 2010-2015
00:41:16 NCL Objectives
00:41:43 NCL Concept of Operations
00:41:48 In Vitro Cascade
00:42:36 NCL Assay Cascade
00:43:03 Nanotech Points of Discussion
00:43:57 Untitled
00:44:34 Voluntary Consensus Standards
00:44:53 The role of ASTM
00:45:24 Standards
00:46:54 See the DLS video
00:47:21 Summary
00:48:33 Selected reference list
00:49:09 Contact Information
One of the great hopes for nanotechnology is in the treatment of cancer. We will look at some of the programs and technologies being explored and the importance of nanotechnology in this area.