New Methods for Characterizing Biomolecules at APGI

APGI/MALVERN Information Day – “New Methods for Characterizing Biomolecules”

Wednesday, January 11, 2017 at the CNAM
Co-organized with APGI and CNAM

With the rapid development of biomolecules in new therapies, innovative characterization techniques are being developed alongside classical techniques (such as size-exclusion chromatography coupled with triple or tetra detection, or the NTA technique, well-suited for measuring exosomes, sub-visible particles, and other types of contaminants, etc.).

This is why the APGI (Association of Industrial Pharmaceutical Technology) and Malvern invite you to an information day on this topic.

It will be a great day with high-level conferences independent of Malvern and industrial testimonials:

• Michel Desmadril (Integrative Biology Institute of the Cell Macromolecule Integration Platform) will discuss the contribution of isothermal microcalorimetry (ITC) to the detection of new therapeutic agents (9:00 AM).
  
  
• Alexandre Chenal (Pasteur Institute – Biochemistry of Molecular Interactions) will give a lecture on the experimental determination of the net charge of proteins and estimation of the number of ligands by measuring electrophoretic mobility (9:45 AM)
  
  
• Didier Clenet (Sanofi Pasteur – Formulation and Stability Platform at Marcy l’Etoile) will discuss the use of nano-DSC for studying the kinetic stability of proteins (11:00-11:45 AM) as well as the contribution of NTA technology (Nanoparticle Tracking Analysis) to vaccine formulation development (2:00 PM)
  
  
• Bertrand Raynal (Pasteur Institute – Molecular Biophysics Platform) will give a lecture on quality control of biomolecules, one of the keys to success: contributions of size-exclusion chromatography and static and dynamic light scattering (11:45 AM).
  
  
• Jean-Bernard Hamel (Becton Dickinson- R&D – Le Pont de Claix) will present on the detection of sub-visible particles in syringes with several techniques (2:45 PM)
  
  
• Arnaud Gissot (University of Bordeaux – INSERM U1212/CNRS 5320) will conduct a comparative study of the granulometry of small organic particles by DLS and Taylor Dispersion (4:00 PM)
  
  
• Jérôme Thiebaud (Sanofi Pasteur – Biochemical and Biophysical Characterization Platform at Marcy l’étoile) will discuss size-exclusion chromatography and quadruple detection as tools of choice for characterizing polysaccharides and glycoconjugates (4:45 PM)

*Coffee breaks and lunch are offered by Malvern. Participation in the day is free for APGI members.