Cyclosporines are immunosuppressant drugs which are often delivered for ophthalmic indications in the form of microemulsions, offering thermodynamic stability, phase transition to a liquid-crystal state, very low surface tension and small droplet size. These features assist ocular absorption and retention of the drug, parameters upon which its efficacy and duration of action depends.

The formulation of ophthalmic emulsions (eye drops) with long shelf life is complicated by the tendency of emulsion droplets to aggregate, particularly in the presence of the polymers that are used to increase formulation stability. 

This application note describes a comprehensive multi-parameter strategy for the characterization of microemulsions, designed to improve the efficiency of the approval process for both innovator and generic ophthalmic emulsions.

Please login or register for free to read more.

ログイン

初めての方

会員登録いただくと、以下のような会員様限定コンテンツを無料でご覧いただけます。

  • 録画版ウェブセミナー、プレゼン資料、動画
  • アプリケーションノート、技術資料、記事、ホワイトペーパー、ソフトウェアダウンロード

加えて、以下の情報が定期的に届くメールニュースにも任意でご登録いただけます。

  • 最新のマルバーン・パナリティカル製品情報、技術情報、分析について学べるセミナー・ウェブセミナー・イベント情報