Ask an Expert! - Ensuring sample integrity during zeta potential measurements

Electrophoretic light scattering (ELS) is a technique for measuring the zeta potential of particle dispersions and macromolecular solutions. Zeta potential is the surface charge that a particle or macromolecule has in a particular medium and can be used to predict dispersion stability and provide information on the surface chemistry of the sample under investigation.

For the majority of applications, the measurement of zeta potential is routine, However, for certain samples which contain delicate material (e.g., proteins) or high ionic strength dispersants (e.g., physiological buffers), the measurements can be more challenging. It is important to ensure that sample integrity is maintained during the measurement and that the results obtained are accurate.

In this webinar, we will discuss practical tips and how to set up measurements to ensure that sample integrity is not compromised when delicate or challenging samples are measured.

Whether you have questions about samples or sample prep, setting up an experiment, or performing analysis, feel free to submit them so that we can deliver the information you require. There’s always more to learn, whether it’s setting up your measurements for quick batch processing, gaining confidence in the quality of your results, or presenting your data in the best format. 

For this webinar, we’ll assume you’ve watched the previous one on the same topic. Don't worry if you missed it or can't remember it – you can watch it back here. 

Don’t forget to bring your questions or submit them by emailing (For inclusion in the webinar presentation, questions and data can be submitted up to 10 days upfront. There is also the opportunity to ask questions on the day.) 

More information: 

This webinar is part of our ongoing ‘Ask an expert’ webinar series. These live webinars are meant for students, researchers, and professors alike who want to sharpen their analytical methods, deepen their knowledge, or find out how to improve their data. 

We’ll provide extensive materials analysis information and answer your most frequently asked questions. In other words, it’s the ultimate way to improve your materials science research and engineering knowledge. 

It’s free to attend any of the classes. For a full overview of the 2022 program, click here

To watch any of last year’s webinars, take a look at the full program recordings here.


  • Mike Kaszuba - Technical Support Manager
  • Tom Mallon - Application Specialist Nanometrics