Date recorded: June 03 2014

Duration: 39 minutes 50 seconds

Determination of the optical properties of organic compounds is important when carrying out laser diffraction particle size measurements. However, many users struggle to obtain realistic values. In this presentation, we present methods for measuring and calculating these important parameters, enabling good laser diffraction particle size measurements to be carried out. In addition, we introduce a new tool available in the Mastersizer 3000 software which aids users in optimising optical property selections.

Table of contents
1. "Optical properties of organic compounds"
00:44
2. "Optical properties of organic compounds"
00:47
3. Abstract
00:31
4. Determination of real part of refractive index
02:13
5. General
01:41
6. We must get the real part right…
00:29
7. Imaginary part robustness - 3 S’s
00:25
8. Determination of imaginary part of refractive indexAlways assumes that real part is known
01:38
9. RI – Becke Lines/Schroeder van der Kolk
01:16
10. Abbe refractometer
00:23
11. Prism & ScaleRI = 1.70 top limit
00:50
12. Saveyn method
00:54
13. Saveyn et alPartec 2001
00:14
14. Saveyn – particle size distribution - robustness
00:47
15. Reject ridiculous solutions
00:23
16. Saveyn gives… (2 methods)
00:45
17. Literature: http://www.guidechem.com/dictionary/137-26-8.html
00:35
18. ChemSketch
00:47
19. Quantitative Structure-Activity Relationships
01:03
20. The Parachor
00:50
21. Density
00:37
22. http://webmineral.com/help/CellDimensions.shtml
00:58
23. RI and density
00:18
24. RI - Density (Gladstone-Dale et al) – ParticlesCIC, Leeds, UKMeasured density 2.674 g/cm3; Therefore: RI = 1.544Formula from plot is approx. RI = 0.195 + 1.03 (theory 1.0)
01:04
25. How could you calculate the RI of a G6 dendrimer?
00:43
26. G6 Dendrimer Zetasizer Nano
00:25
27. G6 dendrimer – RI calculationBased on CMR3 values for atomic refractivities
00:49
28. Robustness – imaginary part of RI
00:32
29. Conclusions - Rawle paper at WCPT7 Beijing
01:04
30. Conclusions - Rawle paper at WCPT7 Beijing
01:16
31. Conclusions - Rawle paper at WCPT7 Beijing
01:06
32. Another material - optical microscope ($800…)
00:47
33. Robustness – imaginary part of RI
01:32
34. Volume concentration (ISO 13320:2009)
01:13
35. Reject poor choices
00:46
36. New Optical Property Optimizer for Mastersizer 3000
00:00
37. The Optimizer – 1.544/0.001
00:57
38. Conversion to number – in line with imaging?
00:36
39. Another material - optical microscope ($800…)
00:29
40. Try again… (0.1)
00:21
41. And again… (0.01) – this agrees with the volume concentration experiment – shape slightly different to MS2000 result: multiple scattering?
00:21
42. 3.0 gives better fit and residual
00:33
43. 0.0003? Doesn’t fit with volume concentration..
00:22
44. So what to do?
00:31
45. Take care with the fit and residual
02:00
46. Summary
00:36
47. Are you a winner or a loser?
00:34
48. Webinar references
00:25
49. Contact Information
01:40