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Malvern Panalytical expands pharmaceutical drug development solutions through the acquisition of Creoptix

Malvern Panalytical, a company providing advanced analysis and services solutions for the pharma drug product development, as well as services and solutions for other industries, has today announced its acquisition of Creoptix AG, a specialist bioanalysis sensor company. The acquisition forms a critical part of Malvern Panalytical’s strategy to expand its capabilities in support of drug discovery.

Industry:
Pharmaceutical
Malvern Panalytical expands pharmaceutical drug development solutions through the acquisition of Creoptix
Application Note

07 January 2022 | English

Biophysical characterization of viral and lipid-based vectors

Characterization of nucleic acid-based vaccines delivered as viral and non-viral vectors requires fit-for-purpose analytics and a significant level of method understanding In this peer-reviewed paper, you’ll discover how first-principle, label-free biophysical techniques can be applied to the characterization of the critical quality attributes of viruses and lipid nanoparticles. You’ll learn: How the combination of complementary label-free biophysical techniques have been successfully used for the characterization of physical and chemical attributes of rAAV and LNPs encapsulating mRNAExplore analytical techniques, including dynamic light scattering (DLS), multiangle-DLS (MADLS), Electrophoretic Light Scattering (ELS), nanoparticle tracking analysis (NTA), multiple detection SEC and differential scanning calorimetry (DSC)How to apply these techniques to measure multiple, critical quality attributes, including particle size distribution, aggregation propensity, polydispersity, particle concentration, particle structural properties and nucleic acid payload

Products:
NanoSight NS300
Technology:
Electrophoretic Light Scattering
Industry:
Pharmaceutical
Biophysical characterization of viral and lipid-based vectors