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Whitepaper

03 December 2021 | English

Eliminate problematic polymorphs and fast-track stable solid forms with X-ray powder diffraction

Progressing drug development without fully understanding the structure and stability of polymorph variants can quickly lead to potential safety, efficacy or quality issues. Gaps in polymorph profiling can also lead to ambiguity in patent applications, which can have disastrous consequences even years into a drug product’s lifecycle. A clear understanding of an API and all its forms - through solid form analysis - could improve the chances of regulatory approval, decrease the time required to get a drug product to market, and protect potential revenues. This guide explores the use of X-ray powder diffraction (XRPD) as a powerful tool to develop and improve pharmaceutical formulations and ensure quality standards are met throughout the drug development workflow.

Products:
Empyrean range
Technology:
Differential Scanning Calorimetry (DSC)
Industry:
Pharmaceutical
Eliminate problematic polymorphs and fast-track stable solid forms with X-ray powder diffraction
Poster

03 December 2021 | English

Epsilon 1 Wells for faster well interventions

On-asset solution for Production Chemistry and Flow Assurance challenges: The Epsilon 1 wells is an on-asset monitoring solution that gives you critical production chemistry and flow assurance data within minutes. It maximizes uptime and production by giving you the ability to make data driven decisions about production parameters for scale-squeezes and other interruptions in real time.

Products:
Epsilon 1 range
Technology:
X-ray Fluorescence (XRF)
Industry:
Oils, Fuels and Chemicals
Epsilon 1 Wells for faster well interventions
Article

03 December 2021 | English

A controlled blend

This article introduces an energy dispersive X-ray fluorescence (EDXRF) spectrometer for on-line elemental analysis in liquid process flows: Malvern Panalytical’s Epsilon Xflow. This technology enables the user to analyze, control and steer liquid-based production processes in real time, thereby optimizing production processes and blending operations. The analytical performance of the on-line spectrometer is demonstrated using two applications: on-line monitoring of the sulfur concentration in diesel to meet sulfur concentration levels prescribed by Euro VI, China VI, Bharat Stage VI, Tier 3 regulations, and the analysis of catalysts poisons in hydrotreating and fluid catalytic cracking (FCC) processes.

Products:
Epsilon Xflow
Technology:
Energy Dispersive X-ray Fluorescence (EDXRF)
Industry:
Oils, Fuels and Chemicals
A controlled blend