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Making shear rheological measurements on samples with a high solids fraction can present difficulties on a rotational rheometer, since the sample can be prone to fracture even at low-medium shear rates. It is possible to extend the measurement range for such samples using a squeeze flow technique which utilizes the advanced axial capabilities of the Kinexus rheometer . .

Products:
Kinexus ultra+
Date:
January 25 2016
Language:
English
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In this application note, we describe a novel method to rapidly measure the size and concentration of Adeno-Associated Virus (AAV), utilizing the Nanoparticle Tracking Analysis (NTA) technique and a gold labeling method. By labeling AAV capsids with small gold nanoparticles, we were able to increase the amount of light scattered by each capsid, enabling rapid NTA characterization to determine the virus concentration and aggregation state. NTA characterization of AAV was previously impossible without gold labeling..

Products:
NanoSight NS300
Date:
March 8 2016
Language:
English
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This application note describes a comprehensive multi-parameter strategy for the characterization of microemulsions, designed to improve the efficiency of the approval process for both innovator and generic ophthalmic emulsions.

Products:
Kinexus range
Date:
June 27 2016
Language:
English
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With the increasing demands on water supplies and tighter regulations, much research is being done on water treatment processes. Subjects of study include improving processes to allow treated water to be used in secondary applications, optimizing filtration processes to remove biological contaminants and reduce membrane fouling, monitoring filter breakthrough to minimize maintenance requirements or contamination, and verifying ability to remove the increasing load of nanoparticulates in the waste water stream. . Numerous technologies exist for monitoring particle size and concentration in the micron size range, but Nanoparticle Tracking Analysis (NTA) is a unique technology that provides greater insight into the sub-micron size range that is so important to many of these advanced water treatment processes..

Products:
NanoSight LM10
Date:
July 26 2016
Language:
English
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