As the Nanoparticle Tracking Analysis (NTA) technique has gained in popularity in recent years, comparison to Dynamic Light Scattering (DLS) results has become more frequent. When comparing results, it is important to understand the differences between the two techniques and what the reported parameters truly mean. This technical note reviews the difference between measures of the center of the distribution (mean and z-average), measures of the width of the distribution (standard deviation and polydispersity index (PDI)) and the different distribution weighting types (number, volume and intensity).

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