Application of Dynamic Light Scattering (DLS) to Protein Therapeutic Formulations: Principles, Measurements and Analysis - 2. Concentration Effects and Particle Interactions

The influence of concentration effects and particle interactions on DLS results is discussed at the example of increasing sample concentration. A roadmap for identifying and distinguishing different types of concentration effects is presented that may influence biotherapeutic product development. [Colloidal stability, Virial effects, hydrodynamic interaction parameter, dynamic Debye plot]

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