Insitec Spray

Robust process particle size analyzer for sprays and aerosols

  • Laser diffraction particle size analyzer
  • Configured for droplets and dry particles
  • Measure between 0.1 - 2500µm

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Overview

Engineered to withstand the rigors of the process environment, Insitec Spray uses laser diffraction technology to measure droplets and dry particles from 0.1 µm to 2500µm. Capable of measuring even highly concentrated sprays and aerosols, Insitec Spray delivers real-time monitoring and control, 24/7.

Insitec Spray particle size analyzers deliver fully automated, in situ, real-time particle size measurement for sprays and aerosols. They are used to monitor conditions in wind tunnels and atmospheric chambers, to characterize domestic aerosols and personal care products, and to monitor batch and continuous processes such as spray drying.

Features

  • Integration with existing control platforms to simplify development of automated control protocols

  • High reliability of >95% with little downtime, minimal maintenance and maximum ROI

  • Easy-to-use software and fully automated operation to minimize training requirements and release operator time

  • Base model hardware manufactured to GAMP5 standards and compatible with CIP/SIP requirements to meet specific manufacturing specifications

Tailored to your requirements

All Insitec installations are tailored to the unique requirements of the application. They range from simple at-line, manually-fed systems to fully automated, validated on-line solutions for continuous monitoring and multivariate control. 

Malvern Panalytical works in partnership with its customers, providing expertise, hardware and software, where and when it’s needed. This ensures cost-effective, successful project implementation and a positive return on investment.

Factors for success

The success of process analysis depends on detailed consideration of three critical components:

  • The process interface
  • Sample measurement
  • Data presentation and use

The process interface

Insitec systems are items of process equipment and operate within the plant environment. Getting the interface between the instrument and the plant right is essential for long-term, trouble-free operation.

Malvern Panalytical has proven technology for a wide range of spray applications. Insitec Spray at-line systems run alongside the process and have a manual interface. For automated continuous operation the Insitec is installed in the process. 

Insitec Spray has flexible configuration options that make the transmitter and detector easy to position around the spray or aerosol with minimal engineering. Both pilot- and commercial-scale applications can be handled. A well-designed in-line interface ensures that the analyzer runs reliably with minimal maintenance without disrupting the process.

Sample measurement

Insitec systems use the technique of laser diffraction to rapidly measure particle size. Working with spray systems, complete particle size distributions are measured in less than a second, giving instantaneous monitoring. Even fine temporal fluctuations in spray patterns can be tracked effectively.

Insitec Spray directly measures the spray or aerosol, which may have a very high particle concentration. Patented multiple scattering algorithms handle the effect of concentration on measured particle size, mathematically correcting for the effect of source light interacting with several particles before detection, not just one; an effect that is more prevalent at high concentrations. The result is reliable particle size information even for the most concentrated of sprays and aerosols.

Insitec produces reliable, timely and complete data, reporting full particle size distributions. These data provide a secure foundation for better process control whether that control is manual or automated.

Data presentation and use

Insitec systems are integrated within the process plant. Typically they are operated from a centralized control room and the measurement results drive routine decision making. Powerful software packages make integration and data interpretation straightforward.

Malvern Link II software provides the functionality required to integrate an Insitec within the existing control system and to automate process control. It allows operation from either a dedicated PC or from existing control mimics. Malvern Link II is not confined only to Insitec integration; it also eases integration with other instrument types, simplifying multivariate control.

RTSizer software presents measurement data in a clear, accessible way. Results reporting can be tailored to industry and customer norms to improve information flow. Insitec data are used to:

  • Improve process understanding
  • Deliver instant upset detection
  • Support comprehensive process optimization
  • Automate process control

Because complete particle size distributions are reported, monitoring and control can be based on whichever size fraction is of interest (e.g. fines, 3-30 µm fraction, amount of material over 200 µm). Insitec data drives optimized manual control strategies and enables automation of process control, delivering substantial economic returns.

Key applications

Insitec Spray is capable of measuring even highly concentrated sprays and aerosols, delivering real-time monitoring and control. 

Flexible configuration simplifies installation on the process with options for: 

  • Fully customized configuration
  • Powder streams
  • Pharmaceutical processes

Specification

System

Measurement type Particle size
Measurement range 0.1 to 2500µm
Measurement principle Laser diffraction
Optical models Mie theory
Accuracy ±2% on Dv(50) reported using the verification reticle

General

Power 100/240V
Enclosure rating IP65
Operating platforms 10 bar (g)
Software RTSizer (for instrument control) Malvern Link II (for system automation and data link)
Maximum distance from instrument to PC 500m (up to 2 km using fiber optics)

Operating environment

Temperature 10°C – 70°C
Humidity 35% - 80% (non-condensing)

Accessories

Insitec Spray customized configuration

Fully customized, reliable, robust particle sizing for sprays and aerosols.

A variable path length particle sizing sensor that offers maximum flexibility for spray and aerosol applications, delivering reliable, continuous monitoring 24/7. Suitable for droplets or particles from 0.1 to 2500µm with an intrinsically safe option for zoned hazardous environments.

Insitec Spray for powder streams

Reliable, robust particle sizing for unconfined powders.

A variable path length particle sizing sensor that offers maximum flexibility for the continuous monitoring of powders which flow freely, unconfined by vessels or pipework. Suitable for measuring particles from 0.1 to 2500µm.

Insitec Spray for pharmaceutical processes

PAT solution for real-time particle size analysis of pharmaceutical sprays.

Engineered to withstand the rigors of the process environment, Insitec Spray for pharmaceutical industry applications provides a robust, proven PAT solution for measuring particles from 0.1 to 2500 µm. Insitec Spray laser diffraction analyzers can be configured to measure sprays and aerosols in most processes, delivering real-time monitoring and control 24/7, with options for gas or dust zoned hazardous environments.

User manuals

Software downloads

19 September 2009

7.40

Insitec 2000 RT Sizer software

  • Maintenance update
7.40

19 June 2007

7.20

Insitec 2000 RT Sizer software

  • Correlation by percentile added to Data Analysis
  • Ability to set particle density remotely
  • Measuring to a file on a network location
  • Files moved to locations accessible by any Windows user
7.20

19 March 2005

7.11

Insitec 2000 RT Sizer software

  • Updated version
7.11

26 April 2023

3.48

Malvern Link II Software

  • Updates the compatibility of Malvern Link II to the Mastersizer software Version 3.88 for use with the Mastersizer Auto-Lab and other automated Mastersizer applications
  • Whilst functionality should be maintained with Insitec RTSizer and other Automated Mastersizer platforms it is recommended to use Malvern Link II v3.47 until full testing of these platforms is completed.
3.48

28 July 2021

3.47

Malvern Link II Software

  • Introduces REST (Representational state transfer) service. 
  • Compatible with RT Sizer software and Mastersizer v.3.72.
3.47

15 July 2021

3.46

Malvern Link II Software

  • Introduction of OPC-UA server 
  • Bug fixes enhancing stability.
3.46

11 November 2020

3.45

Malvern Link II Software

  • Introduces SOP General Action: “Snapshot”. To store a snapshot of all internal IMD data (status, alarms and values) in a file in JSON format. 
  • Bug Fixes
3.45

22 September 2020

3.44

Malvern Link II Software

  • Introduces three new SOP General Actions: “Timestamp”, Set Limits, and Increment.
  • The Timestamp is an action that writes the date and time into a custom variable. 
  • Combined valve switching and confirmation have been implemented.
3.44

16 July 2020

3.43

Malvern Link II Software

  • Introduces Mastersizer 3000 Auto-Lab. 
  • The Zetasizer device driver has been updated is compatible with >8.0 Zetasizer software 
  • Dynamic setting of delay duration implemented. 
  • Bug Fixes
3.43

05 June 2020

3.42

Malvern Link II Software

  • Bug fix enabling updates to IMDdata values from WinWrap script in customer data converter 

3.42

21 April 2020

3.41

Malvern Link II Software

  • External release of MLII Framework update and stability improvements implemented in 3.40 internal release
  • Bug fixes
3.41

20 October 2010

1.41

  • Maintenance update
1.41

20 April 2009

1.40

  • Maintenance update
1.40

20 January 2009

1.39

  • Fast Cleaning Option
  • Alarm Auto Clear Option
1.39

20 July 2008

1.38

  • Configuration automatically saved on exit from software
  • Option to create a measurement file according to Lot number
1.38

20 October 2007

1.37

  • Maintenance release
1.37

20 April 2007

1.36

  • Maintenance release
1.36

20 March 2006

1.35

  • Facility to restrict access at operator level added
1.35

Support

Solutions to maximize the return on your investment

To ensure that your instrument remains in top condition and performs on the highest level, Malvern Panalytical offers a wide range of services. Our expertise and support services assure an optimal functioning of your instrument.

Support

Service for a lifetime

  • Phone and remote support
  • Preventive maintenance and checkups
  • Flexible Customer Care Agreements
  • Performance certificates
  • Hardware and software upgrades
  • Local and global support

Expertise

Adding value to your processes 

  • Sample preparation development/optimization
  • Analytical methodologies 
  • Turnkey solutions for XRD 
  • Operations via IQ/OQ/PQ, quality assurance (GLP, ISO17025) or round robins/inter-laboratory studies
  • Consultancy services

Training and education

  • Training on-site or at our competence centers
  • Broad range of basic and advanced courses on products, applications and software
Robust spray particulate analysis.

Robust spray particulate analysis.

Spray and aerosol particle analysis. Fully automated, in situ, real-time measurement. Tailored to your unique application.

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