This fully automated instrument is designed to allow both particle characterization scientists with limited spectroscopy experience and more experienced spectroscopists to get an in-depth understanding of their particulate samples. 

Key features include:

  • Measures particle size, shape and chemical identity in one platform.
  • Automates Morphologi G3 with Kaiser Optical Systems RamanRxn1™ spectrometer.
  • Integrated dry powder dispersion with accurate dispersion energy control automates sample preparation for consistent measurements of both fragile and robust materials.
  • Versatile sample presentation accessories for measuring suspended and filtered samples.
  • Simple SOP operation from sample dispersion through to size, shape and chemical analysis.
  • Automatic selection, targeting and chemical classification of thousands of individual particles.
  • Export function for third party forensic library investigations.
  • Direct Raman spectrum export to (Bio-Rad) KnowItAll® ID Expert software for spectral library search.
  • Single point manual targeting mode for manual selection of particles for chemical analysis.
  • Powerful and intuitive software interface making both visual and statistical interpretation of your data easier than ever.

The Morphologi G3-ID is ideally suited to solving complex particle characterization problems where component-specific particle size and shape distributions are required. This includes measurement of components within powder blends and suspensions, along with the identification of contaminant or suspicious particles within product formulations.

The measurement workflow can be divided into three distinct steps, each of which can be automated:

  • Sample preparation
    This step is critical to getting good results; spatial separation of individual particles and agglomerates is the goal. The Morphologi G3-ID has an integrated dry powder disperser which makes preparing dry powder samples easy and reproducible. The applied dispersion energy can be precisely controlled, enabling the measurement process to be optimized for a range of material types. Dispersion is achieved without explosively shocking the particles, avoiding the damage of fragile particles while ensuring strongly agglomerated materials are dispersed. Effective dispersion of fibers can also be achieved. Accessories for presenting suspended or filtered samples that fit directly into the Morphologi G3-ID’s automated stage are also available.
  • Particle size and shape measurement
    The instrument automatically measures the size and shape of particles in a dispersed sample in exactly the same manner as the Morphologi G3. This ensures there is no compromise on the reliability of the particle size and shape data, which is not the case with many chemical mapping and imaging techniques.
  • Chemical identification
    The instrument automatically finds particles of interest for chemical identification based on pre-defined classification rules. A Raman spectrum is acquired from the center of mass of each particle. Chemical identification is then achieved based upon established spectroscopic algorithms incorporated within the Morphologi G3-ID software. This allows enumeration of defined classes of particles as well as the reporting of component-specific particle size and shape distributions. Spectra of unknown particles can be directly exported to Bio-Rad’s KnowItAll® ID Expert software for comparison against its Raman library containing over 13,000 spectra.


Static automated imaging combined with Raman spectroscopy
Análisis morfológico:
Static automated imaging
Tamaño de partícula:
1 µm – 1000 µm*
Propiedades medidas de partícula:
Size, shape, transparency, count, location, chemical identification
Parámetros de tamaño de partícula:
Circle equivalent (CE) diameter, length, width, perimeter, area, maximum distance, sphere equivalent (SE) volume, fiber total length, and fiber width
Parámetros de forma de partícula:
Aspect ratio, circularity, convexity, elongation, high sensitivity (HS) circularity, solidity fiber elongation, fiber straightness
Parámetro de transparencia de partículas:
Intensity mean, intensity standard deviation

Sample dispersion

Mecanismo de dispersión:
Sample entrainment, leading to particle shear and particle impaction
Rango de presión de dispersante:
0.5 bar – 5 bar
Precisión de presión de dispersante:
0.1 bar increments
Velocidad de tiempo de inyección:
5 msec - 100 msec
Tiempo de sedimentación de muestra:
1 s - 600 s
Opciones de presentación de muestra:
4-slide holder for standard microscope slides 
2-slide holder for large microscope slides 
25 mm and 47 mm dia. holders for membrane filters
Thin-path wet cell for low volume particle suspensions


Fuente de luz:
White light, brightfield diascopic and episcopic
5M pixel 2592 x 1944 color CCD array
Ancho de pixel:
2.78 µm x 2.78 µm
Sistema óptico:
Nikon CFI 60 brightfield/darkfield system
2.5x, 5x, 10x, 20x, 50x
Tamaño de partícula:

[For fully automated Chemical ID measurements (see Morphologi G3 product page for standard particle size specification)]
2.5x: 100 µm – 1000 µm (nominal)
5x: 25 µm – 420 µm (nominal)
10x: 20 µm – 210 µm (nominal)
20x: 20 µm – 100 µm (nominal)
50x: 1 µm – 40 µm (nominal)


Análisis químico:
Raman spectroscopy
Espectrómetro Raman:
Kaiser Optical Systems Inc. RamanRxn1
Desempeño espectral:
150 cm-1 to 1850 cm-1, 6 cm-1 resolution
Longitud de onda:
785 nm
<500 mW (spectrometer)
> 10 mW nominal (at sample)
Tamaño de punto de laser:
3 µm at 50x magnification
Seguridad de laser:
Class 3B
Método de identificación química:
Spectral correlation
The Morphologi G3-ID and Morphologi G3-ID are protected by copyright and design rights, together with patents based on EP2106536A1 and US8111395B2

Weight and dimensions:

Dimensiones (ancho, fondo, altura):
Main instrument: 440 mm x 760 mm x 750 mm
Dimensiones (ancho, fondo, altura):
Spectrometer: 584 mm x 448 mm x 203 mm
Main instrument: 80 kg approx
Spectrometer: 27.7 kg

Operating environment:

100 V - 240 V ac 50/60 Hz 6.0 A
Temperatura de operación (°C):
+15°C to +30°C
Temperatura de almacenamiento:
-15°C to +30°C
0%–95%, non-condensing


Sample and substrate dependent. Instrument can also be used as a Morphologi G3. See Morphologi G3 page for details on performance capabilities

The characterization of particles in suspension is a subject of interest for a variety of applications. For example, in pharmaceutical products the presence of inherent, extrinsic or intrinsic particles may affect the efficacy or possibly the safety of the drug. In the automotive industry, the presence of particulate contamination in hydraulic fluid power systems interferes with lubrication and causes wear to components. Many standards specify microscopy analysis for the enumeration of foreign particles in suspensions, and define particulate count limits for a given volume of sample.

Malvern Panalytical's range of sample presentation accessories for the Morphologi G3-ID expands the capabilities of this system beyond the characterization of dry sample dispersions. Each accessory fits directly into the Morphologi G3-ID’s automated stage and is easily selectable in the software. KnowItAll® ID Expert software works alongside Morphologi G3-ID software to provide effective support for chemical identification.

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Morphologi G3-ID

Identification software

KnowItAll® ID Expert software platform from Bio-Rad


Bio-Rad’s KnowItAll® ID Expert software platform works seamlessly with Malvern’s Morphologi software to provide rapid identification of your Raman spectra.

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Accessories to use when analyzing particles in suspension

Thin-path wet cell


The thin-path wet cell is designed for both morphological and chemical characterization of up to 100 μL of sample. It is ideal for applications such as the identification of subvisible particles in therapeutics (described by guidance in USP <787> and USP <788>), especially when a traditional membrane filtering approach may risk changing particles of interest, such as protein aggregates.

2-slide and 4-slide holders


‘Sandwiching’ a few μL of a suspension of smaller particles between a microscope slide and a cover slip is a traditional method of sample preparation for microscopy. Samples are presented in this form to the Morphologi G3-ID using either the 2-slide or 4-slide holder. Slides suitable for chemical identification applications are available.

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Accessories to use when analyzing particles captured on a membrane filter

25 mm and 47 mm diameter filter holders


Methods which are used to detect and characterize particles in suspension often rely on filtering the sample in order to capture particles on a membrane filter. Dedicated filter holders (25 mm or 47 mm diameter) and also the 2-slide holder (see above) allow samples on filter membranes to be presented directly to the Morphologi G3-ID for analysis.
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Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.

When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.

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