Suspended Drugs: how to optimize the efficacy of these API's by controlling both size and shape

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00:00:00 Suspension Drug Dosages Particle Characterization by Image Analysis
00:01:50 Suspension Drug Dosages – Particle Characterization by Image Analysis
00:02:21 Agenda:
00:02:54 Suspension Drugs
00:03:50 Traditional Measuring Techniques
00:05:53 Advantages of Image Analysis
00:07:43 Flow Particle Image Analysis with Sheath Flow
00:09:45 Image Archive – Antacid – 10um
00:11:24 API in Suspension Drug Dosage Before U/S Dispersion
00:12:11 API in Suspension Drug Dosage After U/S Dispersion
00:12:20 API, before U/S dispersion
00:13:15 API, after U/S dispersion
00:13:33 Key Morphological Parameters First Steps – Size Parameters: 1. Center of Mass 2. Major Axis 3. Area, Perimeter, Length, Width, Convex Hull, CEDiameter
00:15:36 Key Morphological Parameters
00:16:55 Key Morphological Parameters
00:18:09 Key Morphological Parameters
00:18:56 Key Morphological Parameters
00:19:42 Key Morphological Parameters
00:20:48 How to Gain from Shape Analysis
00:22:03 New Insights with Image Analysis
00:22:32 The Economic Advantages of Image Analysis
00:23:00 Sysmex FPIA 3000
00:23:26 Contact Information
Suspended drugs of the wrong shape - imagine long rods or needles - or not agglomerated to the right degree, can effect the bioavailability and overall efficacy of the API. Flow imaging provides a means measuring and optizing these parameters.