Characterization of Ferritin

The size, molecular weight and charge of ferritin were measured by the Zetasizer Nano. The results confirm that the ferritin is not monomeric, but exists as a mixture of oligomers in the sample analysed. 

Ferritin is the iron (Fe) storage protein inside cells which forms a 24-mers. Molecular weight was larger than the expected 474 kDa, and hydrodynamic size of ~18nm correlated with this finding.

The charge was found to be negative.


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