The molecular weight of proteins, synthetic and natural polymers is a direct indicator of product performance and activity.
Understanding molecular weight determination, absolute molecular weight measurement and other molecular parameters is key to controlling product performance in a wide variety of applications areas including:
Strength, durability and toughness of plastics and other synthetic polymers.
Degradation and release rate of drug delivery polymers.
Performance and mouth-feel of polysaccharides in foods e.g. maltodextrin and other starch derivatives.
Strength and quality of fillers and lubricants in pharmaceuticals and cosmaceuticals e.g. hyaluronic acid and cellulose derivatives.
Efficacy and aggregation state of proteins and biopharmaceuticals e.g. monoclonal antibodies (mAbs).
Malvern Panalytical’s advanced GPC/SEC detectors, which include low angle and right angle light scattering (LALS and RALS) and multi-angle light scattering (SEC-MALS), are designed to measure absolute molecular weight with unparalleled accuracy. The OMNISEC system offers a complete stand-alone solution to measure molecular weight, and the OMNISEC REVEAL detector module can be used to upgrade an existing GPC/SEC system. The SEC-MALS 20 can be added to either of these solutions to add further capabilities to the solution.