Enhancing NTA accuracy and repeatability with flow mode measurements

The standard measurement mode for Malvern’s NanoSight Nanoparticle Tracking Analysis (NTA) technique takes place with the sample static. In that case, the only motion in the analysis is the Brownian motion of the particles. Since NTA is a single-particle technique, the statistical representation of the analysis is increased as more particles are included in the measurement.  Precision and repeatability of concentration measurements are significantly improved when a slow flow is imparted on the sample to ensure that a greater number of new particles flow through the measurement zone and are analyzed during an experiment.


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