Here you can search and access all the content created by Malvern Panalytical scientists and engineers for the benefit of our customers. Below is a summary of the types of information available:

Application notes

Application notes describe the application of one or more of our analytical methods to resolve issues or answer questions.

Technical notes

Technical notes are descriptions of scientific concepts, experimental methods and analyses relating to Malvern Panalytical's solutions.

Articles

Articles are downloadable copies (PDF format) of content that we have had published in scientific media/press.

Whitepapers

Whitepapers are guides that focus on solving specific industry issues, highlighting the pros and cons of various approaches.

Resource Center Search

Free access to exclusive content including webinars, presentations, application notes, technical notes, whitepapers and more. Enter your search term in the box and use the drop down boxes to filter the results.

Reset filters
Items shown: 5 , 10 , 20 , ALL
Sort by: Date or Relevance

Previous page Showing results 6 - 10 of 137 Next page

Analytical QbD (AQbD) promises to extend the rigor and benefits of QbD into the area of analytical method development. Here, Paul Kippax provides an introduction to the methodology involved and takes as an example the application of AQbD to the development of a laser diffraction particle sizing method. .

Products:
Mastersizer range
Date:
March 3 2014
Language:
English
More details

Use of a novel combination of dynamic light scattering and Raman spectroscopy to elucidate the conformational stability and structure of proteins in biopharmaceutical formulations

Products:
Zetasizer Helix
Date:
April 22 2014
Language:
English
More details

Use of DLS combined with Raman spectroscopy to monitor changes in secondary and tertiary protein structural markers together with size changes to more fully understand the unfolding behavior of lysozyme and other proteins.

Products:
Zetasizer Helix
Date:
April 25 2014
Language:
English
More details

Use of combined DLS and Raman spectroscopy to investigate the evolution of aggregation and the unfolding process of BSA under thermal stress.

Products:
Zetasizer Helix
Date:
May 2 2014
Language:
English
More details

Dissecting a ligand into smaller fragments can provide a strategy for analyzing the role of key functional groups in a protein-ligand interaction. Conversely, low-affinity ligand fragments that are able to occupy a receptor-binding site simultaneously, can often be linked together to form high-affinity inhibitors. The key challenge to such studies lies in measuring the thermodynamics of low-affinity interactions. This white paper will address the issues of studying low-affinity systems by Isothermal Titration Calorimetry (ITC). Topics will include working with receptor concentrations below KD (i.e., low c-values), and how displacement techniques can be employed to measure very low affinities while still complying with the c-value rule. Illustrative examples will be drawn from studies with carbohydrate-binding proteins.

Products:
MicroCal PEAQ-ITC
Date:
July 1 2014
Language:
English
More details

Previous page Showing results 6 - 10 of 137 Next page