CubiX³ Pharma offers speed, reliability and reproducible analysis. Results enable manufacturers to maintain consistency in the quality of their product while optimizing production speeds. Equipped with Malvern Panalytical’s X’Celerator, CubiX³ Pharma is the fastest and most precise diffractometer available for production control.

Data and operation traceability in regulated environments

Malvern Panalytical’s Audit Trail software meets today’s requirements for validation of analytical instruments and supports compliancy with 21 CFR Part 11 governing the use of electronic records and electronic signatures.

Installation Qualification (IQ) and Operational Qualification (OQ)

Tools such as Installation Qualification (IQ) and Operational Qualification (OQ) ensure at any time the optimal performance for accurate results and lowest detection limits.

High-speed sample throughput featuring quick turnaround times

Ultra-fast sample loading in combination with a high-speed linear detector such as X’Celerator allow a higher sample throughput that enables the user to control their processes more effectively. Measurement times of 5 minutes can be easily achieved.

Best sensitivity for impurities allows fast process optimization

Optics, optimized for the special requirements of the pharmaceutical industry allow lower detection limits for impurities. This knowledge can be used to optimize drug and formulation development and provides the basis for an efficient production and quality control.

Push-button measurements for easy operation and virtually no learning curve

The Industry software package handles measurement as well as complex calculations for industry-specific parameters. With a push of a button the operator can measure and analyze even unknown samples. 

The Walk-up operator interface enables a fully automated XRD measurement and analysis that allows at any time access for adding new samples, operates also in a regulated environment, and requires no knowledge of XRD to achieve results. 

GeneralSample handling
Goniometer: θ-θ for completely horizontal sample handlingProgrammable spinner
Diffractometer: 200 mm radiusUltra-fast pneumatic loader
Software: Industry, optional with Audit Trail functionality and/or Walk-up package and HighScore Plus64 position X’Changer with 2 x 30 positions plus 4 preferred loading positions
Detector: Xe-filled proportionalX’Handler for belt connection with 2 additional positions
X’Celerator detector (RTMS)Automation possible with any automated laboratory

CubiX³ Pharma




The world’s first 1D silicon strip detector for laboratory X-rays

As the world’s first silicon-based position-sensitive 1D detector for XRD, the X’Celerator is the result of the pioneering development from Malvern Panalytical. With the R&D 100 Award-winning X’Celerator detector you can perform XRD measurements up to 100 times faster than with a traditional point detector, without compromising data quality. With no need for cooling water, liquid nitrogen flow, counting gas or time-consuming calibrations, it is a cost-effective solution.

The X’Celerator is designed exclusively for Malvern Panalytical’s diffractometers for applications in research and industry.

One solution for drug development

The most fundamental applications in XRD are crystallinity determination and the identification or “fingerprinting” of crystalline phases (e.g. polymorphs). Here Malvern Panalytical’s powerful search/match/identification software HighScore Plus works behind the scenes, comparing diffractograms to a reference library or your own private database of reference patterns.