差示掃描量熱儀 (DSC) 是穩定、強大且常用的定性及定量工具，可以幫助我們了解像蛋白質、配體、酵素和微脂體等生物分子的穩定性、熱力學和動力學，這也使其成為生技藥物開發過程的重要角色。本課程分享了 DSC在不同領域的應用實例，讓您了解 MicroCal PEAQ-DSC 能如何幫助您進行候選成份篩選、配方開發、製程或參數優化、穩定性監測、研究生物分子交互作用、研究結構和結構域以及生物相似性等工作，本課程也會和您講述 DSC 在研究、品質管控及驗證程序上的基礎數據解讀知識及實驗技巧。
Differential Scanning Calorimetry (DSC) is a robust and powerful tool for characterizing the properties of biomolecules such as protein, ligand, enzyme, and liposome. It helps us understand their stability, thermodynamics, and kinetics, making it an essential part of biopharmaceutical development processes. By examples in different applications, this video will show you how the MicroCal PEAQ-DSC helps you in candidate selection, formulation development, process or parameter optimization, stability monitoring, biomolecular interactions, structure and individual domain analysis, and biosimilarity assessment. It will also show you the basic concepts of data interpretation and practical tips to make your PEAQ-DSC as a research, quality control, and verification tool.
演講者
- Peter Gimeson - Biosciences Field Application Manager, Malvern Panalytical