Ask an expert! - ITC for organic solvents: Tips for success with this trending application in chemistry and life sciences

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There are increasing interest in Isothermal Titration Calorimetry (ITC) applications that require dissolving the binding partners in an organic solvent. These include studying guest-host chemical reactions, interactions involving nanoparticles, and characterizing normally insoluble materials. For successful results, the ITC experimental protocol with organic solvents requires minor modification of the normal methods with aqueous buffers. This webinar will discuss the best practices for using organic solvents with MicroCal ITC systems, including the PEAQ-ITC, iTC200, and VP-ITC. These suggestions will help improve the data quality and avoid damaging the ITC instrument. 

Presenters include research scientists who routinely incorporate organic solvents in their ITC experiments, as well as ITC experts with Malvern Panalytical. 

Don’t forget to bring your questions or submit them by emailing (For inclusion in the webinar presentation, questions and data can be submitted up to 10 days upfront. There is also the opportunity to ask questions on the day.) 

More information: 

This webinar is part of our ongoing ‘Ask an expert’ webinar series. These live webinars are meant for students, researchers, and professors alike who want to sharpen their analytical methods, deepen their knowledge, or find out how to improve their data. 

We’ll provide extensive materials analysis information and answer your most frequently asked questions. In other words, it’s the ultimate way to improve your materials science research and engineering knowledge. 

It’s free to attend any of the classes. For a full overview of the 2022 program, click here

To watch any of last year’s webinars, take a look at the full program recordings here.


  • Gloria Tobajas Curiel - PhD Student - University of Cambridge, UK 
  • Angus Yeung - PhD Student - University of Birmingham, UK 
  • Raul Pacheco Gomez - Field Application Specialist - Malvern Panalytical 
  • Verna Frasca - Sector Development Manager - Pharma & Food - Malvern Panalytical

More information

Who should attend?

Students and research scientists in academia and the pharmaceutical industry, working in the field of biomolecular science and engineering, who are interested in improving their knowledge with our analytical solutions.

What will I learn?

  • Experimental practicalities as well as how to obtain quality data will be covered.
  • Information on chemical resistance and what solvents to avoid when using an ITC instrument