記録された日時: July 30 2020
Quality by Design (QbD) and in-vitro bio-equivalence (IVBE) describe pathways to develop new and generic topical drug products through the optimization of critical material attributes including particle size.
But how does one measure this property in what is often a highly viscous material? Moreover, what if there are multiple components in a complex formulation?
The answer to the first question is typically found in microscopy, which when performed manually is often a laborious and subjective technique. The answer to the second question can be found in Morphologically Directed Raman Spectroscopy (MDRS), which is quickly gaining prominence as a technology that provides component-specific particle size and shape.
In this webinar, we describe how automated microscopy can allay some of the concerns outlined above and how MDRS can be used to develop, de-formulate, optimize and compare topical drug products.